Page 204 - Biochemistry PharmD General

Complications of Diabetes

A. Alterations in blood sugars: hyperglycemia and hypoglycemia.
B. Macrocirculation (large blood vessels)

1. Atherosclerosis occurs more frequently, earlier in diabetics.
2. Involves coronary, peripheral, and cerebral arteries.
C. Microcirculation (small blood vessels)
1.Affects basement membrane of small blood vessels and
capillaries.
2. Involves tissues affecting eyes and kidneys.

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