Page 26 - controlled drug delievery
P. 26
Cont. Diffusion controlled S.
1-A-Reservoir type
• The rate of drug release is controlled by the insoluble membrane
through which the drug must diffuse.
Water diffusion in
Drug diffusion out
• The diffusion process in membrane controlled systems is
governed by Fick’s diffusion law:
dm = DAK (Ci - C0)
dt h