Page 40 - controlled drug delievery
P. 40
2- Dissolution-controlled Systems.
• A slowly soluble coat or matrix is used instead of insoluble polymers
used in diffusion systems.
• The dissolution process at steady state is described by Noyes- Whitnney
equation:
dc = KA (Cs-C) = D A (Cs-C)
dt h
• Specially suitable for ------------------------------------drugs
• Formulated as either matrix or reservoir systems.
