Page 52 - controlled drug delievery

Characteristics of Osmotically controlled S

• The drug is surrounded by semipermeable membrane and the
release is controlled by osmotic pressure

• Zero order release is possible
• Reformulation is not required for different drugs.
• More expensive than conventional counterparts
• More extensive quality control testing.
• Examples of osmotc controlled devices:

– Verapamil HCl tablets
– Glipizide tablets
– Potassium chloride tablets