Page 23 - Pharmaceutical Analytical Chemistry II - Pharm D Clinical- 07-PA202
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• Completeness of the reaction
The change in the equivalence-point region of redox titration (magnitude
of end point break) becomes larger as the reaction becomes more
complete.
(↑ difference in E0 of the sample and titrant), the more complete is the
reaction.
At least a 0.2 V difference is required for a sharp end point
The redox titration is feasible if the difference in E0 of the redox couples
(sample and titrant) is ≥0.2 V
Detection of the END POINT in redox
titrations
The equivalence point in the redox titration curve is marked as the
steepest point occurs at the rising part of the curve ---- it is
characterized by abrupt change in Esys
End point detection:
• Visual indicators
1. Self-indicators
2. Specific indicators
3. Redox indicators
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