Page 55 - phytochemistry I - PharmD Clinical
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Supercritical fluid extraction (SFE)
Effective methods for the isolation of high-quality essential oils.
Separating any essential oil from the matrix using supercritical fluid as
extracting solvent, ex. SC CO2.

In this method the plant material is placed in a pressure vessel and pumps
a particular liquefied gas such as carbon dioxide through it at a specific
pressure and temperature simultaneously above its critical point. The
pressure forces the solvent into the cell walls of the botanical and extracts
the desired constituents rapidly.
Examination of V.O.
• To evaluate the quality of the plant species as well as the raw material
which will be used in commercial preparations.
• To differentiate between genuine and adulterated oil.
• Physical examination of volatile oil is very important.

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