Page 183 - BIOCHEMISTRY II
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• After carbohydrate meal Glucose is transported to portal blood to
the liver.
• About 40% of glucose passes to the blood circulation stimulating
insulin secretion and taken up by brain, muscles, adipose tissue and
liver. The remaining 60% of glucose is taken up by the liver and
converted by Glucose-6-phosphate by glucokinase.
• G-6-P will has one of the following fates in the liver:
– Conversion to glycogen (Glycogenesis) stimulated by insulin.
– Conversion to fatty acids (Lipogenesis) stimulated also by
insulin.
3- Renal Regulation
• Circulating blood glucose is filtered in glomerular filterate and
reabsorbed again by certain tubular enzymes. This saves blood
glucose from loss in urine. 187
