Page 184 - BIOCHEMISTRY II
P. 184

• If blood glucose levels exceeds certain limits (average 180 mg/dl),
    glucose will increase in glomerular filterate and exceeds the
    capacity of tubular enzymes to reabsorb it. Thus glucose appears
    in urine (glycosuria).

• This limit is called renal threshold for glucose re-absorption: It is
    the blood glucose level above which glucose appears in urine
    (average 180 mg/dl).

• Low renal threshold: where glucose appears in urine even when
    blood glucose levels are low (may be just 100 mg/dl). This occurs
    in:

     – Normally in some people due to defective tubular enzymes for
        glucose reabsorption.

     – In 20% of pregnant women.

                                                                                                                                       183
   179   180   181   182   183   184   185   186   187   188   189