Page 82 - MNU-PM503 Parasitology practical book

Pharm D- Clinical Pharmacy Program Third Level Parasitology and virology (PM503)

Case study (17):

A 37-year-old man was admitted to the hospital for fever and an inflamed foot.

He had spent the previous three months touring South America, southern and eastern

Africa, and Kathmandu. Ten days before admission, he visited game reserves in

Tanzania, where he reported multiple tsetse fly bites. Six days later, he developed pain

in the left foot and high fever. The next day, he noted progressive swelling on the

dorsum of the foot and he was evaluated at a clinic in Katmandu.

A malaria smear was negative and he was prescribed cephalexin. He continued

to have intermittent high fever (to 41°C [105.8°F]) and developed vomiting, headache,

myalgia, and a diffuse rash. A repeat malaria smear was negative, but his white cell

count was 4000 per mm3 with 10% band forms. He returned to the United States and

was admitted to the hospital. A shallow ulceration was present on his left instep,

encircled by bullae at the margin and surrounded by purple discoloration. The foot

lesion was 5 cm in diameter.

QUESTIONS

1. Which protozoan parasite is causing this infection?

2. Which form of this parasite is infectious? Draw it.

3. Name the habitat of this parasite.

4. How is this parasite transmitted?

5. Which condition might result as a sequence of this infection?
6. Describe the pathogenicity of this protozoon.

7. How is the laboratory diagnosis of this infection made?
8. How is this infection treated?

9. How can this infection be prevented and controlled?

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