Page 202 - MNU microbiology theoritical 2025
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General Microbiology & Immunology (PM 401) Second level Semester 4 2024/2025
• but they intercalate between adjacent base pairs in the replication bubble
during DNA synthesis causing frameshift mutation during replication.
3- Base analogues.
They are compounds that resemble purine or pyrimidine bases so they are
incorporated into DNA during replication in place of natural bases.
For example: 5- bromouracil.
General Microbiology & Immunology (PM 401) theoretical handbook Page 191
