Page 198 - MNU microbiology theoritical 2025

General Microbiology & Immunology (PM 401) Second level Semester 4 2024/2025

2- Frame Shift mutation

- occurs when one or two bases are added or deleted.

- This will change the reading frame starting from

the location of addition or deletion and extending

downstream.

- the amino acid sequence downstream of the

mutation site differs from the original amino acid

sequence leading to complete loss of normal

protein structure and function

General Microbiology & Immunology (PM 401) theoretical handbook Page 187