Page 161 - The Miracle in the Cell
P. 161

HARUN YAHYA

                                            PREPARATORY
                                            CONVERSIONS
                                                         Pyruvic acid
                                                   NAC +          Co Enzyme A
                                                                   CO 2


                                                          Acetyl CoA
                                              Krebs cycle
                                                                   2
               Figure 8.6                                        H O
               During the second stage of the
               aerobic respiration pathway,                         Co enzyme A
               pyruvate enters the mitochondri-
               on, where it is broken down           Oxaloacetate  Citrate
               completely. Carbon dioxide and
               water are obtained from the       Malate             Isocitrate
               resulting carbon and oxygen
               atoms-the source of the carbon
               dioxide breathed out through the                   x-ketoglutarate
               lungs.                           Fumarate
               As the diagram shows, before
               entering the Krebs cycle, the
               pyruvate is completely converted
               into acetyl coenzyme A, which    Succinate
               then enters the Krebs cycle and                     Succinyl CoA
               combines with oxaloacetate (The  Co
               Krebs cycle got its name from the  Enzyme A
               scientist who worked on it in the
               1930s). The Krebs cycle has three
               functions: The first is to obtain
               H+ and electrons to transfer to
               coenzymes such as NAD and
               FAD. The second is production
               of ATP by phosphorylation. And
               the third is to convert the many
               different substances in the center
               of the cycle, obtained after many
               steps by many different
               enzymes, back into oxaloacetate.
               If this reconversion was not
               done, and there is only a limited
               amount of oxaloacetate in the
               cell, respiration would soon stop.
               But because of the extraordinary measures taken by God, oxaloacetate is always
               regenerated. The incredible reactions that take place in the second step produce
               only two ATPs. But many of the coenzymes, H+ ions and electrons produced in
               this step are used in the third and final stage of respiration.






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