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Level two – Semester 4 - PharmD      Biochemistry-II PB-403 (Practical course)     2024/2025


                                      2.  Electrocardiographic findings (ECG changes).

                                      3.  Coronary angiography.

                                      4.  Its  diagnosis  is  confirmed  by  the  characteristic
                                         changes  in  plasma  enzyme  activities  or  troponin
                                         levels.


                         Cardiac Function Markers



                   The  cardiac  markers  leak  out  of  injured  myocardial  cells  through  the

                   damaged cell membranes into the bloodstream.




                                                                 Time After            Duration of
                                             Reference
                    Cardiac Marker                             Infarction: 1            Elevation
                                                                              st
                                               Range
                                                               Elevation (hr)             (days)

                                                <170
                      Myoglobin                                       2-3                    1
                                               ng/mL


                       Creatine
                      kinase MB             <10 ng/mL                 4-6                   2-3

                        (CKMB)

                        Cardiac
                                               <0.07
                      troponin I
                                               ng/mL
                         (cTnI)
                                                                      4-6                  7-10
                        Cardiac
                                                < 0.1
                      troponin T               ng/mL
                         (cTnT)





















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