Page 77 - Practical DF2 Corrected (2)

Pharm D Clinical Pharmacy program 2024-2025 Level 2, Semester 2 Pharmaceutical Dosage Forms II (PT 405)

Toothpaste

• Toothpaste, also called dentifrice, is essential to daily oral hygiene routine.
• They are pastes, gels or powders that help remove plaque, a film of bacteria

that forms on teeth and gums.
• It improves the mechanical brushing and cleaning power of a toothbrush.

• Toothpaste ingredients:

1) Abrasive:
o Mild abrasives to remove debris and residual surface stains.
o Examples: calcium carbonate, dehydrated silica gels, hydrated aluminum
oxides, magnesium carbonate, phosphate salts and silicates.

2) Fluoride:
o It strengthens tooth enamel and remineralize tooth decay.

3) Humectants:
o They prevent water loss in the toothpaste. Examples include glycerol,
propylene, glycol and sorbitol.

4) Thickening agents:

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