Page 8 - P4304.1-V92_PS-Magazine-December 2023 PRINT

Enhance flexibility
in your dispensary
with Golden Tote
Our semi-automated dispensing solution is revolutionising
the way dispensing doctors operate, offering a digital
system that unlocks your business’s full potential while
enhancing flexibility in your dispensary. This innovative
system has demonstrated its ability to enhance safety,
streamline operations, and elevate precision, all wrapped
in an easily manageable package that seamlessly
integrates into your dispensing processes.
Golden Tote not only presents an opportunity to embrace
automation but also enables a stronger connection with your
patients. By leveraging barcode scanning technology, our “pick to
prescription” application simplifies prescription assembly directly
from the PHOENIX tote. This eliminates the need for double-
handling stock from totes, saving you valuable time spent on
tasks like invoice verification, order placement, and frequent stock
management chores such as rotation and date checks.
Due to this the interest in Golden Tote this year has been nothing
short of remarkable! Many have expressed a keen desire to witness
a live demonstration of our solution aboard our vans. You can still
schedule visits to your practice in the coming year, to book a visit
and for more details, get in touch with your dedicated Dispensing
Doctor Account Manager.
Golden Tote alleviates you
from the dispensary bench,
allowing you to focus on
providing care to your
community, both now and
well into the future.
8 PS Magazine | Golden Tote
P4304.1-V92_PS-Magazine-December 2023.indd 8
P4304.1-V92_PS-Magazine-December 2023.indd 8 09/11/2023
Buy direct online at PSUK.co.uk
09/11/2023
PSUK is pleased to offer a 40% discount
on Sereflo pMDIs for dispensing practices
Product NHS List price 1 PSUK discount Saving
Sereflo pMDI
25/125mcg £14.99 40% £5.99
Sereflo pMDI £19.99 40% £7.99
25/250mcg
Sereflo pMDI can offer a 25mcg salmeterol with 125 or 250mcg fluticasone
combination more cost-effectively than the market-leading competitors,
Seretide® and Sirdupla® (salmeterol/fluticasone). Plus, you can take
1-3
advantage of significant additional savings with the PSUK discount.
Sereflo pMDI is indicated for use in adults with asthma 18 years of age and older only. 4,5
Sereflo pMDI is indicated in the regular treatment of patients with moderate to severe asthma
where use of a combination product (long-acting β2 agonist and inhaled corticosteroid)
is appropriate:
- patients not adequately controlled on a lower strength corticosteroid combination product 4,5
or
- patients already adequately controlled on an inhaled corticosteroid in a mid or
high strength and a long-acting β2 agonist. 4,5
Seretide is a trademark of GSK. Sirdupla is a registered trademark of Mylan.
pMDI = pressurised metered dose inhaler.
Sereflo Metered Dose Inhaler (salmeterol xinafoate/fluticasone with caution in patients with severe cardiovascular disorders or heart rhythm abnormalities and in
®
propionate) patients with diabetes mellitus, thyrotoxicosis, uncorrected hypokalaemia or with a predisposition to
Prescribing Information low levels of serum potassium. Prescribers should also be aware of the risk of adrenal suppression
and acute adrenal crisis which may occur in patients on prolonged treatment with high doses of
Please consult the full Summary of Product Characteristics (SmPC) before prescribing inhaled corticosteroids. Systemic effects may occur with any inhaled corticosteroid and it is important
Sereflo 25 microgram (μg) salmeterol xinafoate /125 μg or 250 μg fluticasone propionate per actuation therefore, that the patient is reviewed regularly and the dose of inhaled corticosteroid is reduced to the
pressurised inhalation, suspension. For both dose strengths the equivalent delivered dose per
actuation is 21 μg of salmeterol and the delivered fluticasone propionate is 110 μg, for 125 μg dose lowest dose at which effective control of asthma is maintained. Visual disturbances may be reported
with steroid use. Patients presenting with blurred vision or other visual disturbances should be
strength and 220 μg, for 250 μg dose strength. INDICATIONS: For use in adults with asthma 18 years
of age and older only. Sereflo is indicated in the regular treatment of patients with moderate to severe considered for referral to an ophthalmologist. Drug Interactions: Concomitant use should be avoided
with; non-selective and selective β blockers, ritonavir and other potent/moderate CYP3A inhibitors,
asthma where use of a combination product (long-acting β2 agonist and inhaled corticosteroid) is
unless potential benefit outweighs the risk. Particular caution is advised in acute severe asthma
appropriate: patients not adequately controlled on a lower strength corticosteroid combination product as hypokalaemia may be potentiated by concomitant treatment with xanthine derivatives, steroids
or patients already adequately controlled on an inhaled corticosteroid in a mid or high strength and
and diuretics. See the SmPC for further information on contraindications and precautions.
a long-acting β2 agonist. POSOLOGY AND ADMINISTRATION: Patients should be instructed
in the proper use of their inhaler (see SmPC and patient information leaflet). Recommended PREGNANCY AND LACTATION: Balance risks against benefits. UNDESIRABLE EFFECTS:
Adverse events which have been associated with salmeterol/fluticasone propionate include: Very
doses in adults 18 years and older - Two inhalations of 25μg salmeterol and 125 μg or 250 μg
common; nasopharyngitis and headache; Common; candidiasis of the mouth and throat, pneumonia,
fluticasone propionate twice daily. A short-term trial of salmeterol and fluticasone propionate may be
considered as initial maintenance therapy in adults with moderate persistent asthma for whom rapid bronchitis, hypokalaemia, throat irritation, hoarseness/dysphonia, sinusitis, contusions, muscle
cramps, traumatic fractures, arthralgia and myalgia. For other adverse events please consult the full
control of asthma is essential. In these cases, the recommended initial dose is two inhalations of 25
μg salmeterol and 50 μg fluticasone propionate twice daily. Note: Sereflo is not available in a lower SmPC. MARKETING AUTHORISATION HOLDER & PL NUMBERS: Cipla (EU) Ltd. Dixcart House,
Addlestone Road, Bourne Business Park, Addlestone, Surrey KT15 2LE. PL 36390/0237 and PL
strength product containing salmeterol 25 μg and fluticasone propionate 50 μg. Therefore, when
initiating therapy, or when it is appropriate to titrate down to a dose below 125 μg, an alternative 36390/0238. Legal category: POM. NHS Cost 25 μg/125 μg 1x 120 dose MDI £14.99 and 25 μg/250
fixed-dose combination of salmeterol and fluticasone propionate containing a lower dose of the μg 1x 120 doses MDI £19.99. Date of last revision: April 2020.
inhaled corticosteroid is required. Use of a spacer device; where required in those with difficulties in
coordinating actuation of the inhaler with inspiration of breath, it is recommended ONLY for higher
strength Sereflo containing salmeterol 25 μg and fluticasone propionate 250 μg. Patients should Adverse events should be reported. Reporting forms and information can
continue to use the same make of spacer device (Volumatic or the AeroChamber Plus) as switching be found at www.mhra.gov.uk/yellowcard or search for MHRA Yellowcard
between spacer devices can result in changes in the dose delivered to the lungs. See the SmPC
for further information on initiation, titration down and spacer use. CONTRAINDICATIONS: in the Google Play or Apple App Store. Adverse events should also be
Hypersensitivity to the active substances or to any of the excipients. SPECIAL WARNINGS AND reported Cipla (EU) Ltd on 0800 0472144, drugsafety@cipla.com
PRECAUTIONS: Sereflo should not be used to treat acute asthma symptoms for which a fast- and
short-acting bronchodilator is required. Patients should be advised to have their inhaler to be used
for relief in an acute asthma attack available at all times. Patients should not be initiated on Sereflo References.
during an exacerbation, or significantly worsening or acutely deteriorating asthma. Serious asthma- 1. Dictionary of medicines and devices (dm+d), available at https://www.nhsbsa.nhs.uk/pharmacies-gp-
related adverse events and exacerbations may occur with Sereflo. Patients should be asked to practices-and-appliance-contractors/dictionary-medicines-and-devices-dmd (accessed August 2022).
continue treatment but to seek medical advice if asthma symptoms remain uncontrolled or worsen 2. British National Formulary, Medicinal forms, available at
after initiation. Treatment should not be stopped abruptly due to risk of exacerbation. Therapy should https://bnf.nice.org.uk/medicinal-forms/fluticasone-with-salmeterol.html (accessed August 2022).
be down-titrated under physician supervision. All inhaled medication containing corticosteroids 3. MIMS.co.uk (accessed August 2022).
should be administered with caution in patients with active or quiescent pulmonary tuberculosis and 4. Sereflo 25 microgram/125 microgram. Summary of Product Characteristics.
fungal, viral or other infections of the airway. Salmeterol and fluticasone propionate should be used 5. Sereflo 25 microgram/250 microgram. Summary of Product Characteristics.
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