Page 34 - P4304.1-V102_PS Magazine - Nov 24
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Inclisiran (Leqvio) and


              Drug Tariff Part VIIIC



              By Caroline Pond








                                                              Part VIIIC – Arrangements of
                                                              payment for products supplied
                                                              free of charge or products with
                                                              a nominal price







              In September 2021, the Drug Tariff was                Inclisiran is a cholesterol lowering
              updated to include a new section, Part                treatment indicated for adults with primary
              VIIIC. Part VIIIC sets out arrangements               hypercholesterolaemia (heterozygous familial
              of payment for products with a                        and non-familial) or mixed dyslipidaemia.
                                                                    Novartis is the manufacturer, and they are
              nominal price (i.e where the purchase                 working collaboratively with NHSE&I to
              price of the product is significantly                 improve patient pathways to support improved
              lower than its NHS list price).                       lipid management, which is one of the
                                                                    priorities set out in the NHS Long Term Plan.
              Products listed in Part VIIIC are available at
              nominal prices or free-of-charge because              Inclisiran has been identified by NHSE&I as a
              of commercial deals in place between                  treatment it wishes to adopt systematically
              the manufacturer or supplier and NHS                  and at scale to help tackle cardiovascular
              England/ NHS Improvement (NHSE&I).                    disease (CVD) in a large high-risk patient
              These arrangements allow manufacturers to             population who are unable to reach their
              supply a drug to the NHS at a reduced cost            LDL-C goals on maximum tolerated lipid
              compared to the published NHS list prices             lowering therapies such as statins. To achieve
              as detailed in the Dictionary of Medicines            the scale and volumes required to positively
              and Devices (dm+d).                                   impact a nation’s cardiovascular health
                                                                    outcomes, the initiation and management of
              What types of products are                            this treatment will be predominantly carried
              listed in Part VIIIC?                                 out within a primary care setting, hence you

              Part VIIIC  includes products that are                are seeing prescriptions for Inclisaran or its
                                                                    brand name Leqvio..
              available from a manufacturer or supplier at
              a nominal price that is significantly below           Usually dispensing contractors would be
              the NHS list price for the product because of         reimbursed the NHS list price for Inclisiran if
              a commercial arrangement between NHSE&I               it was listed in Part VIIIA of the Drug Tariff or
              and the manufacturer or supplier of the               at the Brand price for Leqvio which currently
              product.                                              stands at £1987.36 (Sept 24).
              One of those items is Inclisiran (Leqvio)             As it would not represent value for money
              and I know, from the number of emails I am            for the NHS and the taxpayer to reimburse
              receiving, this is catching some of you out           contractors the NHS list price for Leqvio/
              as we begin to process more prescriptions in          Inclisiran and in order to implement this
              primary care.                                         treatment at an affordable price and limit





              34     P S M a g a z i n e |  I n c l i s i r a n (L e q v i o ) a n d D     B u y d i r e c t o n l i n e a t  P S U K . co . u k
              34
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                     PS Magazine | MDS Terms Informationrug Tariff Part VIIIC
                                                                                                                 09/10/2024   14:34:58
         P4304.1-V103_PS Magazine - November 244.indd   34                                                       09/10/2024   14:34:58
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