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2 mg/5 ml
Boosting your margin with Numark own brand (400 mcg/ml)
We’re proud to offer the largest own brand range available in wholesale, with 350 high- strength
quality, low-priced products tailored for pharmacies and exclusive to Numark members. By The first non-branded 2 mg/5 ml
choosing to retail Numark branded products alongside leading brands, you can boost your
margin by up to £800 a month! glycopyrronium bromide oral solution
Huge savings with Discount Partners
An opportunity for adolescents to continue their treatment into adulthood
Our Numark Discount Partners proposition connects you with a variety of carefully
reviewed and vetted suppliers, offering discounts on products and services to support your For the symptomatic treatment of severe sialorrhoea (chronic
daily business needs. pathological drooling) due to chronic neurological disorders of
childhood-onset in patients aged 3 years and older.
1
Whether you need packaging, trays, bottles, or cartons for your dispensary, pharmacy
refrigeration, office equipment, shop floor retail products, staff training support, or help
setting up services in your pharmacy, our Discount Partners suppliers are here to help. Colonis Glycopyrronium Bromide 2 mg/5 ml Oral Solution
gives patients the opportunity to continue their stable dose
By the end of 2024, we welcomed 12 new Numark Discount Partner suppliers and into adulthood. 1
introduced two additional insurance products under Numark Insurance. Members can
save up to £597 a month with the top 10 suppliers and collectively saved £1.4 million last • The 2 mg/5 ml solution is available in 60 ml and 250 ml bottles.
year, thanks to our extensive network of suppliers. See what’s available to you on your
Dashboard! • Sugar-free, strawberry flavour – strawberry is the most popular
flavour with children. 2
Generating additional revenue by delivering private services • A formulation suited for children with swallowing issues. 3
Private services can offer you a way to diversify your revenue streams beyond traditional • Licensed for use with nasogastric and/or PEG tubes. 1
NHS prescriptions, bringing several key benefits. PIP Codes: 128-0841 (60 ml), 128-0833 (250 ml)
Paid services can significantly boost your income and increase footfall by attracting Colonis Glycopyrronium Bromide Oral Solution 2 mg/5 ml is now
more patients, who may also purchase additional items during their visits. Additionally, available to order via Phoenix
private services enhance patient loyalty by meeting a broader range of healthcare needs,
fostering lasting relationships, and encouraging repeat visits and word-of-mouth referrals.
Through our support, resources, and discounted equipment, you can offer various private PRESCRIBING INFORMATION inhaled anaesthetics. May delay absorption of other medication. Concurrent use with slow-
dissolving tablets of digoxin, atenolol or metformin may result in increased serum levels of these
Please consult the Summary of Product Characteristics (SmPC) before prescribing.
services: Product name: Glycopyrronium Bromide 2 mg/5 ml Oral Solution medicines. Use with parasympathomimetics may antagonise the effect.
Adverse effects:
Composition: Each 5 ml contains 2 mg of glycopyrronium bromide Serious: Allergic reaction, seizure (worsening), transient bradycardia, angle-closure glaucoma,
Indications: Symptomatic treatment of severe sialorrhoea (chronic pathological drooling) due to urinary retention (common), pneumonia (common), pyrexia (common), behavioural
• Vaccinations and immunisations, like flu, travel, private COVID-19, and HPV vaccines, chronic neurological disorders of childhood-onset in patients aged 3 years and older. changes (very common)
can also enhance income. You could potentially earn £350 a month from five private Dosage and administration: Dosing is based on the weight of the child. Using the graduated Very common: Dry mouth, constipation, diarrhoea, vomiting, flushing, nasal congestion, reduced
bronchial secretions. Consult the SmPC for further details and for other adverse reactions.
syringe provided, initiate dosing at 0.02 mg/kg three times daily and titrate in increments of
pneumococcal vaccinations. 0.02 mg/kg every 5-7 days. Adjust dose to achieve optimal symptomatic control with minimal NHS price: 60 ml: £76.80, 250 ml: £320
adverse effects. The maximum recommended dosage is 0.1 mg/kg three times daily not
exceeding 1.5-3 mg per dose based on weight. Refer to dosing table (Table 1) in Summary of Legal category: Prescription Only Medicine
• Travel health services, including consultations, vaccinations, anti-malarial treatments, Product Characteristics. Dose should be given one hour before or two hours after meals. For oral Marketing Authorisation Holder: Colonis Pharma Limited, 25 Bedford Square, Bloomsbury,
London, WC1B 3HH, United Kingdom
use and use via nasogastric & PEG feeding tubes.
and health kits, can bring in an average of £380 profit per popular destination per Contraindications: Hypersensitivity to glycopyrronium bromide or excipients; angle-closure MA number: PL 41344/0071
patient. glaucoma; myasthenia gravis; pyloric stenosis; paralytic ileus; prostatic enlargement; urinary Job number: GB-CPL-066-001
retention; severe renal impairment (eGFR < 30 ml/min/1.73 m , including those with end-stage
2
renal disease requiring dialysis); intestinal obstruction; pregnancy & breastfeeding; potassium Date of preparation: December 2024
• Specialised clinics for weight management, smoking cessation, sexual health, allergy chloride solid oral dose products; other anticholinergic drugs. Contraindicated during pregnancy
and whilst breastfeeding.
management, and aesthetic treatments can further increase profitability, with private Warnings and precautions: Not recommended in children under 3 years and should not be used Adverse events should be reported. Reporting forms and information can be found
at: https://yellowcard.mhra.gov.uk/ or search for MHRA Yellow Card in the Google Play or
weight management services alone offering earnings between £984 and £1,524 per in children with mild to moderate sialorrhoea or in patients over 65 years. Use with caution in Apple App Store. Adverse events should also be reported to Colonis Pharma Limited via
children with compromised blood brain barrier. Reduced dose should be considered for patients
Clinigen E-mail: drugsafety@clinigengroup.com
with renal failure. Use with caution in gastro-oesophageal reflux disease, ulcerative colitis,
patient. pre-existing constipation, acute myocardial infarction, hypertension, conditions characterised Fax number: +44 (0) 1932 824284
by tachycardia (including hyperthyroidism, cardiac insufficiency, cardiac surgery), coronary
artery disease, cardiac arrhythmias, patients receiving inhalation anaesthesia. Diarrhoea may Abbreviation
be an early symptom of incomplete intestinal obstruction, especially in patients with ileostomy PEG, percutaneous endoscopic gastronomy.
By embracing the diverse opportunities available and fully utilising the benefits of your or colostomy, and treatment with this drug would be inappropriate and possibly harmful. As References
glycopyrronium bromide inhibits sweating, patients with increased temperature should be
Numark membership, your pharmacy can thrive amidst financial challenges. These observed closely. In high environmental temperature, heat prostration can occur. Avoid repeated 1. Colonis Pharma Ltd. Glycopyrronium Bromide 2 mg/5 ml Oral Solution Summary of Product
Characteristics. Available from: https://www.medicines.org.uk/emc/.
or large doses in patients with uraemia. Patients with fructose intolerance should not take this
strategies help you manage the rising costs of National Insurance and the National Living medicine due to presence of sorbitol. The product contains sodium propyl parahydroxybenzoate 2. Generation R. What flavour would children choose for their medicines? Available from: https://
generationr.org.uk/what-flavour-would-children-choose-for-their-medicines/
(E217) and sodium methyl parahydroxybenzoate (E219) which may cause allergic reactions
[Accessed January 2025].
Wage, while also ensuring long-term sustainability and growth. Together, we can foster a (possibly delayed). Treatment should be evaluated in the event of constipation, overheating, 3. Batchelor HK and Mariott JF. Formulations for children; problems and solutions. Br J Pharmacol.
urinary retention, pneumonia, allergic reaction, pyrexia, very hot weather, changes in behaviour.
community that’s not only resilient but also flourishing. Let’s continue to work hand-in- Safety data beyond 24 weeks are not available. Treatment should be kept as short as possible. 2015;79(3):405–418.
May produce drowsiness or blurred vision, thus patients should not operate machinery.
hand towards creating thriving community pharmacies that meet the evolving needs of Drug interactions: Combinations with drugs with antimuscarinic effects (e.g. amantadine, © Colonis Pharma Limited 2025
Registered in England & Wales No. 05486832. For more information please view our Privacy
our patients, enhancing both care and profitability. tricyclic antidepressants, antihistamines, clozapine; disopyramide; MAOIs, nefopam; memantine, Policy. VAT Registration No. 862418028. Registered office: Colonis Pharma Ltd, 25 Bedford Square,
phenothiazines) may add to adverse effects and can also lead to confusion in the elderly. Use
with corticosteroids may result in increased intraocular pressure. There are specific interactions Bloomsbury, London, WC1B 3HH.
with domperidone, metoclopramide, levodopa, haloperidol; nitrates; topiramate, zonisamide; January 2025 | GB-CPL-066-002
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