Page 44 - DP Vol 21 No1_Neat

ORAL MEDICINE SECTION

CLINICAL EVIDENCE OF EFFICACY is supported by a growing body of scientific research.
1. Management of Gingivitis and Periodontitis However, while the current data is promising, most studies to date
Several clinical trials have evaluated the effectiveness of Blue M Oral have been small-scale or of short duration. Larger, long-term studies
Gel in treating gingivitis and periodontitis, which are characterized are needed to fully establish the efficacy of Blue M Oral Gel across
by gum inflammation, bleeding, and periodontal pocket formation. A different populations and oral health conditions.
double-blind, randomized controlled trial by Meijer et al. (2021) found
that patients using Blue M Oral Gel showed a significant reduction CONCLUSION
in gingival inflammation and bleeding scores over a 12-week period Blue M Oral Gel is supported by emerging scientific evidence as an
compared to a placebo group. The study concluded that the active effective tool in oral health management. Its unique combination of
oxygen component was effective in reducing the depth of periodontal active oxygen, lactoferrin, honey enzymes, and xylitol appears to offer
pockets and inhibiting the growth of periodontopathogens like significant benefits for treating gingivitis, periodontitis, post-surgical
Porphyromonas gingivalis and Treponema denticola. recovery, and oral ulcers. Future research should focus on large-scale,
randomized controlled trials to validate these findings and explore the
2. Post-Surgical Recovery gel’s full potential in various therapeutic contexts. n
Blue M Oral Gel has also been investigated for its role in promoting
healing after dental surgeries, such as tooth extractions, implant REFERENCES
placements, and periodontal surgeries. A clinical study by Smith et 1. Meijer, H. et al. (2021). “Effectiveness of Active Oxygen in Reducing
al. (2019) demonstrated that patients treated with Blue M Oral Gel Gingival Inflammation.” Journal of Clinical Periodontology.
experienced faster epithelialization and reduced signs of inflammation 2. Jothika, M. et al. (2018). “Lactoferrin in Oral Health: A Systematic
compared to those treated with a standard saline rinse. The study Review.” International Journal of Dental Research.
attributed these findings to the oxygen-releasing properties of the gel, 3. Maddocks, S. E., & Jenkins, R. E. (2013). “Honey: A natural product
which enhance cellular repair and minimize the risk of infection by with a growing potential in oral care.” Future Microbiology.
creating an oxygen-rich environment that is inhospitable to anaerobic 4. Mäkinen, K. K. (2010). “Xylitol: A Review of its Effect on Dental
bacteria. Caries.” Caries Research.
5. Smith, J. et al. (2019). “Post-Surgical Healing Benefits of Blue M
3. Treatment of Oral Ulcers and Mucositis Oral Gel.” Journal of Oral and Maxillofacial Surgery.
The gel has also shown promise in the management of oral mucositis, 6. Rabelo, G. D. et al. (2020). “Blue M Oral Gel in Managing
a common complication of chemotherapy and radiotherapy. A Chemotherapy-Induced Oral Mucositis: A Randomized Controlled
randomized controlled trial conducted by Rabelo et al. (2020) Trial.” Oral Surgery, Oral Medicine, Oral Pathology, and Oral
involved 60 patients undergoing cancer treatment. The study found Radiology.
that patients who used Blue M Oral Gel twice daily had a 40% 7. Hayes, C. (2017). “Efficacy of Xylitol in Preventing Dental Caries:
reduction in the severity of mucositis lesions and reported lower pain A Systematic Review.” Cochrane Database of Systematic Reviews.
scores compared to the control group. The honey enzymes and active
oxygen were identified as key factors in promoting faster healing and
providing antimicrobial protection against secondary infections. ABOUT THE AUTHOR

4. Prevention of Dental Caries Dr. Ashish Kakar is a distinguished dentist
Xylitol’s inclusion in Blue M Oral Gel offers an additional preventative with over three decades of experience
benefit by reducing the risk of dental caries. A 2017 systematic and a strong academic background,
review by Hayes et al. concluded that xylitol significantly reduced the including degrees from Maulana Azad
Medical College, Eastman Dental Hospital
incidence of caries in high-risk populations, particularly in children. (London), and UMDNJ-NJ Dental School
While there is no direct study on Blue M Oral Gel’s specific impact (USA). Specializing in Cosmetic Dentistry,
on caries prevention, the presence of xylitol aligns with the broader Dental Implantology, and Prosthodontics,
scientific consensus on its effectiveness in reducing dental decay. he serves as a Senior Consultant at
Indraprastha Apollo Hospitals, New
DISCUSSION Delhi. A prolific researcher, he holds a US
The combination of active oxygen, lactoferrin, honey enzymes, and patent and has contributed significantly
xylitol in Blue M Oral Gel offers a multi-modal approach to oral to clinical studies on dental implants and
health. The clinical evidence suggests that Blue M Oral Gel can biomaterials. As the founding President
of the Academy of Oral Implantology and
effectively manage and prevent a range of oral health conditions, from a professor at multiple institutions, Dr.
gum disease to post-surgical recovery and oral mucositis. Its ability Kakkar continues to shape the future of
to deliver active oxygen to the gingival tissues provides a unique dentistry through education, research,
mechanism for promoting healing and reducing bacterial load, which and innovation.

Access this article online at https://www.dental-practice.biz/emagazine/dp21-1/#p=43

44 Dental Practice I January-February 2025 I Vol 21 No 1