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ORAL MEDICINE SECTION

BLUE M ORAL GEL: A RESEARCH-BASED

ANALYSIS OF ITS EFFICACY IN ORAL HEALTH

Ashish Kakar

ABSTRACT
Blue M Oral Gel is a specialized oral healthcare product
formulated to promote gum health, accelerate wound
healing, and provide antimicrobial effects through its
active oxygen content. This article provides a critical
analysis of the scientific literature regarding the efficacy
of Blue M Oral Gel and its core components—active
oxygen, lactoferrin, honey enzymes, and xylitol. The
article discusses the mechanisms of action, examines
the clinical evidence, and evaluates the potential of
Blue M Oral Gel as a therapeutic agent in oral care.

INTRODUCTION
Oral diseases, such as periodontitis, gingivitis, and
oral ulcers, are prevalent conditions affecting millions
of people worldwide. Effective management of these
conditions is critical, as they are linked to systemic
health issues, including cardiovascular disease,
diabetes, and respiratory infections. Blue M Oral Gel,
which leverages a combination of active oxygen and
other bioactive ingredients, has been proposed as a therapeutic agent A 2018 study by Jothika et al. showed that lactoferrin supplementation
for enhancing oral health. This article reviews the existing research in oral care products significantly reduced the levels of Streptococcus
on the ingredients and formulation of Blue M Oral Gel to assess its mutans and Candida albicans, two pathogens commonly associated
effectiveness in promoting oral health and treating oral diseases. with oral infections.

KEY INGREDIENTS AND THEIR MECHANISMS OF ACTION 3. Honey Enzymes: The honey-derived enzymes in Blue M Oral Gel,
1. Active Oxygen: Active oxygen, in the form of stabilized oxygen, particularly glucose oxidase, produce low concentrations of hydrogen
is a core ingredient in Blue M Oral Gel. It releases molecular oxygen peroxide, an antimicrobial agent that can eliminate bacteria and fungi.
(O₂) when applied, enhancing the oxygenation of tissues. Studies Honey has long been used in wound care for its antibacterial and anti-
have shown that increased oxygen levels in the gingival tissues inflammatory properties. A study by Maddocks and Jenkins (2013)
promote collagen synthesis, angiogenesis, and wound healing. Active highlighted honey’s effectiveness in reducing biofilm formation and
oxygen is particularly effective against anaerobic bacteria, such as bacterial load in chronic wounds. When used in the oral cavity, these
Porphyromonas gingivalis and Fusobacterium nucleatum, which are enzymes provide a continuous, low-level antimicrobial effect, which
common culprits in periodontal disease. The antimicrobial action of helps control bacterial populations without causing resistance or
oxygen-releasing compounds has been documented in several studies, significant tissue irritation.
which suggest that elevated oxygen levels can disrupt bacterial cell
walls, inhibit biofilm formation, and enhance immune cell function. 4. Xylitol: Xylitol is a sugar alcohol that has been extensively researched
for its anti-cariogenic properties. It inhibits the growth of Streptococcus
2. Lactoferrin: Lactoferrin is an iron-binding glycoprotein that has mutans, a primary pathogen involved in tooth decay, by disrupting its
demonstrated potent antibacterial, antiviral, and antifungal properties. energy production processes. A meta-analysis conducted by Mäkinen
It is naturally present in saliva and plays a critical role in the body’s et al. (2010) confirmed that xylitol can reduce the incidence of
immune response to pathogens. Research indicates that lactoferrin dental caries by up to 59% when used regularly over six months. The
can reduce microbial adherence and inhibit the growth of pathogens incorporation of xylitol in Blue M Oral Gel contributes to a reduction
by depriving them of iron, which is essential for bacterial proliferation. in the overall bacterial load, promoting a healthier oral environment.

ARTICLE CITATION
Ashish Kakar (2025). Blue M Oral Gel: a research-based analysis of its efficacy in oral health. Dental Practice, 21(1), 43-44
Dental Practice I January-February 2025 I Vol 21 No 1 43