Page 30 - Practical-organic-3

Activity of 3-Methyl-pyrazolinone Synthesis

1. How to synthesize the following structure?

2. Complete the missing parts about 3-methyl-pyrazolinone mechanism.

3. 3-Methyl-pyrazolinone synthesis requires the elimination of …………. then

…………molecule.

4. In 3-methyl-pyrazolinone synthesis, heating is necessary for the reaction. (T/F)

5. Why cooling by an ice bath is essential in 3-methyl-pyrazolinone synthesis.
……………………………………………………………………………………………
……………………………………………………………………………………………

6. Mention one commercial drug containing a 3-methyl-pyrazolinone nucleus & its
uses.
……………………………………………………………………………………............

…………………………………………………………………………………….............
…………………………………………………………………………………………….
…………………………………………………………………………………….............

…………………………………………………………………………………….............
7. What is the name of 3-methyl-pyrazolinone synthesis reaction?
……………………………………………………………………………....…………….

30