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Mansoura National University
Pharm D-Clinical Pharmacy Program Level 1 Pharm. Anal. Chem. 1 (PC 101)
Natural Acid-Base Indicators
• There are a lot of natural acid-base indicators:
- Red cabbage.
- Turmeric.
- Tea.
- Rose petals.
- Artichoke.
- Grape juice.
- Blueberry……
Acid Base Titration Curves
❖ Titration curve is the curve obtained by plotting pH of the titrated solution (y-axis)
against the volume of the titrant added (x-axis).
❖ The titration curve is characterized by its sigmoid shape
(S-shaped).
❖ The midpoint of the vertical part of the curve corresponds to
the equivalence point.
❖ The shape of the titration curve depends on:
(1) Nature of the titrated solution and the titrant. {strong or weak}
(2) Concentration of the titrated solution and the titrant.
{ concentration
height of the vertical part }
❖ The titration curve helps in studying the titration reaction and selecting a suitable
indicator.
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