Page 36 - PBA Medicine list - edition 5_SW_Neat
P. 36
By Ghezal Zobair and Abdul Basit
Generic Name: Terbinafine
Brand names: Lamisil
Side effects/precautions:
Blood and lymphatic system disorders. Transient decrease in haematocrit, haemoglobin, leucocytes.
Uncommon: anaemia.
Very rare: haematological disorders such as neutropenia, agranulocytosis, pancytopenia,
thrombocytopenia.
Gastrointestinal disorders. Very common: nausea, vomiting, flatulence, mild abdominal discomfort,
abdominal cramps, anorexia, diarrhoea, dyspepsia/gastritis, belching, abdominal distension,
decreased appetite.
Uncommon: taste disturbances, including taste loss, which usually recover within several weeks after
discontinuation of the drug. Isolated cases of prolonged taste disturbances have been reported. A
decrease of food intake leading to significant weight loss was observed in very few cases.
Before prescribing terbinafine tablets, liver function tests should be performed since hepatotoxicity
may occur in patients with and without pre-existing liver disease.
Interactions:
Inhibitors of cytochrome p450, contraceptive pill
Reasons for interactions:
Not available
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