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Isocyanates

▪ Irritate the mucous membranes of the eyes, gastrointestinal and

respiratory tracts.

▪ Direct skin contact can cause contact dermatitis and

inflammation.

▪ Can sensitize workers, making them subject to severe asthma

attacks if exposed again.

▪ There is evidence that both respiratory and dermal (skin)
exposures can lead to sensitization; usually over a period of

months or years, however sensitization can occur after a single
exposure.

▪ Once sensitized, any exposure, even to levels below the

occupational exposure limit can produce a life-threatening asthma
attack.

▪ Exposure must be kept As Low As Reasonably Achievable

(ALARA).