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MSCs transplantation for osteoarthritis treatment
Supporting information
S1 Fig. A funnel plot of VAS, WOMAC, Lequesne, IKDC, Lysholm, and Tegner scores (tif)
generated by Review Manager Version 5.0.
(TIF)
S2 Fig. Language edit certification (tif).
(PDF)
S1 File. PRISMA 2009 checklist.
(DOC)
Acknowledgments
This research was supported by the Scientific Research Subject of the Heilongjiang Province
Health Department (2012–301). The funders had no role in study design, data collection and
analysis, decision to publish, or preparation of the manuscript.
Author Contributions
Conceptualization: MY.
Data curation: LY LL.
Formal analysis: LB.
Funding acquisition: CL.
Investigation: LY LL.
Methodology: LY LL.
Project administration: CL.
Resources: ST.
Software: LY LL.
Supervision: CL.
Validation: ST.
Visualization: LY.
Writing – original draft: MY.
Writing – review & editing: CL.
References
1. Reissis D, Tang QO, Cooper NC, Carasco CF, Gamie Z, Mantalaris A, et al. Current clinical evidence
for the use of mesenchymal stem cells in articular cartilage repair. Expert Opin Biol Ther. 2016; 16
(4):535–57. https://doi.org/10.1517/14712598.2016.1145651 PMID: 26798997
2. Gupta PK, Das AK, Chullikana A, Majumdar AS. Mesenchymal stem cells for cartilage repair in osteoar-
thritis. Stem Cell Res Ther. 2012; 3(4):25. https://doi.org/10.1186/scrt116 PMID: 22776206
3. Freitag J, Bates D, Boyd R, Shah K, Barnard A, Huguenin L, et al. Mesenchymal stem cell therapy in
the treatment of osteoarthritis: reparative pathways, safety and efficacy-a review. BMC Musculoskelet
Disord. 2016; 17:230. https://doi.org/10.1186/s12891-016-1085-9 PMID: 27229856
4. Uth K, Trifonov D. Stem cell application for osteoarthritis in the knee joint: A minireview. World J Stem
Cells. 2014; 6(5):629–36. https://doi.org/10.4252/wjsc.v6.i5.629 PMID: 25426260
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