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%u010ceskoslovensk%u00e1 fyziologie 73/2025 %u010d. 2 31Editorial ............................................................................................................ 29P%u00f8ehledn%u00e9 %u00e8l%u00e1nkyAhmed Mohamed Abdelhamid Ibrahim, Tumisang Edward Maseko, Zuzana %u010cervinkov%u00e1, Moustafa ElkalafInterakce kostern%u00edch sval%u016f a jater p%u0159i steatotick%u00e9m onemocn%u011bn%u00ed jater spojen%u00e9m s metabolickou dysfunkc%u00ed ....................................................... 32 Barbora Ben%u010di%u010dov%u00e1Extracelul%u00e1rne pasce neutrofilov v patogen%u00e9ze COVID-19 .......................... 37Kamil Javorka, Andrea %u010calkovsk%u00e1V%u00fdzvy IUPS: Men%u00ed sa postavenie a obsah fyziol%u00f3gie v %u010dase? ........................ 50Zden%u011bk Wurst, Barbora Bir%u010d%u00e1k Kuchtov%u00e1, Jana Mrz%u00edlkov%u00e1, Ale%u0161 Barto%u0161, Ibrahim Ibrahim, Edvard Ehler, Petr Geier, Petr ZachAlzheimerova choroba %u2013 sou%u010dasn%u00fd stav pozn%u00e1n%u00ed, klinick%u00fd obrazonemocn%u011bn%u00ed, diagnostika s akcentem na mo%u017en%u00fd p%u0159%u00ednos vyu%u017eit%u00ed DTI traktografie ................................................................................... 56Richard Rokyta, V%u00e1clav Hole%u010dekVoln%u00e9 radik%u00e1ly, antioxidanty a redoxn%u00ed potenci%u00e1l .......................................... 63Jind%u0159ich Mourek, Jaroslav Pokorn%u00fd, Enik%u0151 Ra%u010dekov%u00e1, Marcela Marton%u010d%u00edkov%u00e1Hologenom %u2013 interakce lidsk%u00e9ho genomu, mikrobiomu a mitochondri%u00ed .... 69Editorial ............................................................................................................ 29ReviewsAhmed Mohamed Abdelhamid Ibrahim, Tumisang Edward Maseko, Zuzana %u010cervinkov%u00e1, Moustafa ElkalafInteraction of skeletal muscles and liver in metabolic dysfunction-associated steatotic liver disease ............................................... 32 Barbora Ben%u010di%u010dov%u00e1Neutrophil extracelullar traps in the pathogenesis of COVID-19 ................ 37Kamil Javorka, Andrea %u010calkovsk%u00e1IUPS challenges: Does the position and scope of physiology change over time? ............................................................................................. 50Zden%u011bk Wurst, Barbora Bir%u010d%u00e1k Kuchtov%u00e1, Jana Mrz%u00edlkov%u00e1, Ale%u0161 Barto%u0161, Ibrahim Ibrahim, Edvard Ehler, Petr Geier, Petr ZachAlzheimer%u00b4s disease %u2013 current state of knowledge, clinical picture of the disease, diagnosis with an emphasis on the possible benefit of using DTI tractography ............................................................................... 56Richard Rokyta, V%u00e1clav Hole%u010dekFree radicals, antioxidants and redox potential ............................................. 63Jind%u0159ich Mourek, Jaroslav Pokorn%u00fd, Enik%u0151 Ra%u010dekov%u00e1, Marcela Marton%u010d%u00edkov%u00e1Hologenome %u2013 interaction of human genome, microbiome and mitochondria ............................................................................................. 69OBSAHOBSAHCONTENTSRo%u010dn%u00edk 73 / 2025 / %u010d%u00edslo 2%u00c8asopis vych%u00e1z%u00ed 2%u00d7 ro%u010dn%u011bPovoleno Ministerstvem kulturypod %u010d. MK %u00c8R E 6338ISSN 1210-6313 (Print) ISSN 2570-9178 (Online)%u00c8asopis je v pln%u00e9m zn%u011bn%u00ed vystaven na adrese:www.tigis.czVych%u00e1z%u00ed ve spolupr%u00e1ci s %u00c8eskou fyziologickou spole%u010dnost%u00ed %u00c8LS JEP.VydavatelPod Pramenem 1140 00 Praha 4e-mail: info@tigis.czI%u00c8O: 48033961Z%u00e1stupce vydavateleIng. Veronika K%u00f6hlerov%u00e1Kancel%u00e1%u0159e vydavatelstv%u00edKe %u0160kolce 64/6111 01 Praha 10 - Doln%u00ed M%u011bcholupytel.: 274 008 500e-mail: info@tigis.czRedakce %u00e8asopisuJana Banduri%u010dov%u00e1tel.: 274 008 500e-mail: banduricova@tigis.czJazykov%u00e1 korekturaPhDr. Zuzana P%u0159ibylov%u00e1Podklady pro inzerciJana Banduri%u00e8ov%u00e1tel.: 274 008 500e-mail: banduricova@tigis.czTechnick%u00e9 parametry inzercetiskov%u00e9 pdf A4 (210 %u00d7 297 mm) + 5 mm na spadCMYK a o%u0159ezov%u00e9 znakyP%u00f8edplatn%u00e9 %u00e8asopisuMilu%u0161e Loudov%u00e1 tel.: 274 008 500e-mail: loudova@tigis.czTiskTIGIS, spol. s r.o.DistribuceMailFinish a.s., Praha %u00c8esk%u00e1 po%u0161ta, s.p.Vydavatel nenese odpov%u00ecdnost za %u00fadaje a n%u00e1zory autor%u00f9 jednotliv%u00fdch %u00e8l%u00e1nk%u00f9 ani inzer%u00e1t%u00f9. Sou%u00e8asn%u00ec si vyhrazuje pr%u00e1vo na drobn%u00e9 stylistick%u00e9 %u00fapravy %u00e8l%u00e1nk%u00f9 a na jejich zve%u00f8ejn%u00ecn%u00ed na internetu.V%u0161echna pr%u00e1va vyhrazena. %u017d%u00e1dn%u00e1 %u00e8%u00e1st nesm%u00ed b%u00fdt reprodukov%u00e1na tiskem, fotografickou cestou, po%u00e8%u00edta%u00e8ov%u00fdmi soubory dat nebo jin%u00fdmi zp%u00f9soby bez p%u00f8edchoz%u00edho p%u00edsemn%u00e9ho svolen%u00ed vydavatele.Anglick%u00fd text neproch%u00e1z%u00ed jazykovou korekturou vydavatelstv%u00ed na p%u0159%u00e1n%u00ed v%u011bt%u0161iny autor%u016f.%u010cESKOSLOVENSK%u00c1FYZIOLOGIE