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Factors Affecting Functional Mobility and Lower Extremity
Strength in Patients with Knee Osteoarthritis
Weerapong Seehapanya*
Department of Physical Medicine and Rehabilitation, Prasat Hospital
*Corresponding Author E-mail: seehapanya.wee@gmail.com
Objective: Abstract
Knee osteoarthritis (OA) is a widespread degenerative joint disorder that significantly
impacts mobility and strength, leading to disability. In Thailand, knee OA affects 45% of the
population over 50 years, and globally, it affects 22.9%. This condition results in symptoms
such as pain, stiffness, and muscle weakness, which restrict daily activities and functional
mobility. This study aimed to explore the factors affecting functional mobility and lower
extremity strength in patients with knee OA.
Methods: A cross-sectional study was conducted at Prasat Hospital in Surin Province and Sena
Hospital in Phra Nakhon Si Ayutthaya Province, Thailand, involving 100 participants over
50 years with a diagnosis of knee OA, according to the American College of Rheumatology
criteria. Functional mobility was assessed using the Timed-Up-and-Go (TUG) test, while
lower extremity strength was evaluated with the 30-second Chair Stand Test (30s-CST).
Pain levels were measured using the Numerical Rating Scale (NRS). Demographic and
clinical data were collected, and linear regression analysis was performed to determine key
predictors of functional mobility and strength.
Results: Results revealed that age and pain levels were significant predictors of both functional
mobility and strength. Functional mobility (TUG) worsened with increasing age and pain
levels, while strength (30s-CST) decreased with higher pain and older age. No significant
effects were found for body mass index (BMI) or gender.
Conclusion: The factors affecting functional mobility and lower extremity strength in patients with knee
OA including age and pain scale. These findings highlight the importance of addressing
pain management and age-related declines in functional interventions for this population.
82 Joint Conference in Medical Sciences 2025

