Page 20 - Practical-workbook-organic-3 isa
P. 20
Procedure of 4-Hydroxy-phthalazinone Synthesis
In a 250 ml stoppered flask:
◼ At room temperature, add 0.75 gm of phthalic anhydride, then add 5 ml of
acetic acid.
◼ Then add 0.25 ml of hydrazine hydrate (2-4 drops) to the stirred mixture.
◼ Reflux using a condenser and water bath for 20 min.
◼ After completion of the reaction, cool and pour 25 ml of water into the
reaction mixture for purification.
◼ Filter to get white ppt of 4-hydroxy-phthalazinone.
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