Page 52 - Quanta BioDesign Catalog 5-17-18
P. 52

®
        dPEG  Based Chemical Modification Reagents                              Reactivity: Converting an Amine to a Latent Thiol
        Reactivity: Converting an Amine to a Latent Thiol
                                                                           ®
                                    ®
                           dPEG -SATA (S-acetyl-dPEG -NHS ester)
                                      x
                                                                            x


















              Product #                                Description                                100 mg   1000 mg
                                                                ®
                                                 ®
               10181                          dPEG 4-SATA (S-acetyl-dPEG 4-NHS ester)              $235   $1250


                                                              ®
                                         Mol. Wt.: 421.46; single compound; dPEG  Spacer is 16 atoms and 18.3 Å
                                                                ®
                                                 ®
               10184                          dPEG 8-SATA (S-acetyl-dPEG 8-NHS ester)              $350   $1250


                                                              ®
                                         Mol. Wt.: 597.67; single compound; dPEG  Spacer is 28 atoms and 32.5 Å
                                                 ®
                                                                ®
               10852                         dPEG 12-SATA (S-acetyl-dPEG 12-NHS ester)             $400   $1300


                                         Mol. Wt.: 773.88; single compound; dPEG  Spacer is 39 atoms and 46.8 Å
                                                              ®
                                                                ®
                                                 ®
               10188                         dPEG 24-SATA (S-acetyl-dPEG 24-NHS ester)             $550   $1600


                                                              ®
                                         Mol. Wt.: 1302.51; single compound; dPEG  Spacer is 76 atoms and 89.1 Å
        References:
                                        nd
             Greg T. Hermanson, Bioconjugate Techniques, 2  Edition, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; ISBN-10: 0-12-370501-0). References to
                                        ®
             SATA, which can be directly applied to the dPEG  pegylation versions: a) general description and use, pg. 71; b) modification of antibodies, pg. 795; c) modification of amines on
             nucleotides and DNA probes, pg. 984 ; and d) modification of enzymes, avidin and streptavidin with,  pg. 90,909, and 919.
                                        rd
             Greg T. Hermanson, Bioconjugate Techniques, 3  Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See chapter 18, Discrete PEG Reagents, pp.787-821, for a full
                         ®
             overview of the dPEG  products.
                                   Products Protected under U.S. Patents # 7,888,536 & 8,637,711

















                   For technical questions, please call 614-792-2958 or contact info@quantabiodesign.com        46
   47   48   49   50   51   52   53   54   55   56   57