Page 52 - Quanta BioDesign Catalog 5-17-18
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dPEG Based Chemical Modification Reagents Reactivity: Converting an Amine to a Latent Thiol
Reactivity: Converting an Amine to a Latent Thiol
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dPEG -SATA (S-acetyl-dPEG -NHS ester)
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Product # Description 100 mg 1000 mg
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10181 dPEG 4-SATA (S-acetyl-dPEG 4-NHS ester) $235 $1250
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Mol. Wt.: 421.46; single compound; dPEG Spacer is 16 atoms and 18.3 Å
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10184 dPEG 8-SATA (S-acetyl-dPEG 8-NHS ester) $350 $1250
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Mol. Wt.: 597.67; single compound; dPEG Spacer is 28 atoms and 32.5 Å
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10852 dPEG 12-SATA (S-acetyl-dPEG 12-NHS ester) $400 $1300
Mol. Wt.: 773.88; single compound; dPEG Spacer is 39 atoms and 46.8 Å
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10188 dPEG 24-SATA (S-acetyl-dPEG 24-NHS ester) $550 $1600
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Mol. Wt.: 1302.51; single compound; dPEG Spacer is 76 atoms and 89.1 Å
References:
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Greg T. Hermanson, Bioconjugate Techniques, 2 Edition, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; ISBN-10: 0-12-370501-0). References to
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SATA, which can be directly applied to the dPEG pegylation versions: a) general description and use, pg. 71; b) modification of antibodies, pg. 795; c) modification of amines on
nucleotides and DNA probes, pg. 984 ; and d) modification of enzymes, avidin and streptavidin with, pg. 90,909, and 919.
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Greg T. Hermanson, Bioconjugate Techniques, 3 Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See chapter 18, Discrete PEG Reagents, pp.787-821, for a full
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overview of the dPEG products.
Products Protected under U.S. Patents # 7,888,536 & 8,637,711
For technical questions, please call 614-792-2958 or contact info@quantabiodesign.com 46