Page 56 - Quanta BioDesign Catalog 5-17-18
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        dPEG  Based Chemical Modification Reagents                              Reagents to Extend Carboxyl with a dPEG  Spacer

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                                             Azido-dPEG -OH
                                                                  x



                                                                                                -dPEG ®  -OH
                                                                  Cu(I)                      N        x
                   Click:                    +   N -dPEG ® x -OH
                                                  3
                                                                                          N  N
                                     e.g., Dmt-Cl                   (reduction)
                     N -dPEG ® x -OH              N -dPEG ® x -O-Dmt               NH -dPEG ® x -O-Dmt
                                                   3
                                                                                      2
                      3

               Product #                              Description                            100 mg   1000 mg

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                 10541                              Azido-dPEG 4-OH                           $100     $150


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                                        Mol. Wt.: 219.24; single compound; dPEG  Spacer is 14 atoms and 15.3 Å.
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                 10542                              Azido-dPEG 8-OH                           $200     $450

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                                        Mol. Wt.: 395.45; single compound; dPEG  Spacer is 24 atoms and 29.5 Å
                                                           ®
                 10340                              Azido-dPEG 12-OH                          $225     $550



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                                        Mol. Wt.: 571.66; single compound; dPEG  Spacer is 37 atoms and 43.0 Å
                                                           ®
                 10543                              Azido-dPEG 24-OH                          $325     $800



                                                            ®
                                       Mol. Wt.: 1100.29; single compound; dPEG  Spacer is 72 atoms and 86.7 Å
                                                           ®
                 10544                              Azido-dPEG 36-OH                          $350     $950


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                                       Mol. Wt.: 1628.92; single compound; dPEG  Spacer is 108 atoms and 129.7 Å
        References:
                                       rd
            Greg T. Hermanson, Bioconjugate Techniques, 3  Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See chapter 18, Discrete PEG Reagents, pp.787-821, for a full
            overview of the dPEG  products.
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                                   Products Protected under U.S. Patents # 7,888,536 & 8,637,711





















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