Page 62 - Quanta BioDesign Catalog 5-17-18
P. 62
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dPEG Based Crosslinking Reagents Heterobifunctional Reagents: Amine and Thiol Reactive
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4-formyl-benzamido-dPEG -TFP ester
x
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Convert an AMINE to a dPEG containing ALDEHYDE,
reactable with an aminooxy or hydrazide compound!
Aldehydes (latent) are common in
carbohydrates, carbohydrate containing
proteins, and other oxidizable matrices;
and can be incorporated using reagents
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like the 4-FB-dPEG x TFP esters (amine
reactive).
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Aminooxy-dPEG s with a LABEL - Quanta
has available a BIOTIN label; PN 11112 is
perfect for making your own.
Product # Description 100 mg 1000 mg
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10081 4-formyl-benzamido-dPEG 12-TFP ester $200 $1250
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Mol. Wt.: 897.90; single compound; dPEG Spacer is 46 atoms and 49.3 Å
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10082 4-formyl-benzamido-dPEG 24-TFP ester $275 $1500
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Mol. Wt.: 1426.53; single compound; dPEG Spacer is 83 atoms and 93.0 Å
References:
nd
Greg T. Hermanson, Bioconjugate Techniques, 2 Edition, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; ISBN-10: 0-12-370501-0)., See pp.
276-335 for general description and use of heterobifunctional crosslinkers, and the specific sample protocol for SPDP and LC-SPDP on pp. 286-288. See Greg’s extensive
index on pg. 1192-1193 for references to a number and range of applications and their respective protocols.
rd
Greg T. Hermanson, Bioconjugate Techniques, 3 Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See chapter 18, Discrete PEG Reagents, pp.787-821,
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for a full overview of the dPEG products.
Products Protected under U.S. Patents # 7,888,536 & 8,637,711
To place an order, call 614-792-2958 or visit www.quantabiodesign.com 56