Page 62 - Quanta BioDesign Catalog 5-17-18
P. 62

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        dPEG  Based Crosslinking Reagents                                    Heterobifunctional Reagents: Amine and Thiol Reactive

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                           4-formyl-benzamido-dPEG -TFP ester
                                                                          x



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                                  Convert an AMINE to a dPEG  containing ALDEHYDE,
                                  reactable with an aminooxy or hydrazide compound!





















                  Aldehydes (latent) are common in
                   carbohydrates, carbohydrate containing
                   proteins, and other oxidizable matrices;
                   and can be incorporated using reagents
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                   like the 4-FB-dPEG x  TFP esters (amine
                   reactive).

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                  Aminooxy-dPEG s with a LABEL - Quanta
                   has available a BIOTIN label; PN 11112 is
                   perfect for making your own.






               Product #                            Description                            100 mg    1000 mg

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                10081                      4-formyl-benzamido-dPEG 12-TFP ester             $200      $1250




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                                      Mol. Wt.: 897.90; single compound; dPEG  Spacer is 46 atoms and 49.3 Å
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                10082                      4-formyl-benzamido-dPEG 24-TFP ester             $275      $1500




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                                      Mol. Wt.: 1426.53; single compound; dPEG  Spacer is 83 atoms and 93.0 Å
        References:
                                        nd
             Greg T. Hermanson, Bioconjugate Techniques, 2  Edition, Elsevier Inc., Burlington, MA 01803, April, 2008 (ISBN-13: 978-0-12-370501-3; ISBN-10: 0-12-370501-0)., See pp.
             276-335 for general description and use of heterobifunctional crosslinkers, and the specific sample protocol for SPDP and LC-SPDP on pp. 286-288.  See Greg’s extensive
             index on pg. 1192-1193 for references to a number and range of applications and their respective protocols.
                                        rd
             Greg T. Hermanson, Bioconjugate Techniques, 3  Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See chapter 18, Discrete PEG Reagents, pp.787-821,
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             for a full overview of the dPEG  products.
                                 Products Protected under U.S. Patents # 7,888,536 & 8,637,711

                       To place an order, call 614-792-2958 or visit www.quantabiodesign.com               56
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