Page 64 - Quanta BioDesign Catalog 5-17-18

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dPEG Based Crosslinking Reagents Heterobifunctional Reagents: Amine and Thiol Reactive

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Phthalimidooxy-dPEG -NHS ester
x

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A New dPEG Reagent for Stable Oxime
Conjugation Systems!

Aldehydes (latent) are common in
carbohydrates, carbohydrate containing
proteins, and other oxidizable matrices;
including most native antibodies and many
enzymes, e.g. HRP. The amines from the

lysines in proteins can also be converted to
aldehydes and incorporated using reagents
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like the 4-FB-dPEG x TFP esters (amine
reactive). See PN’s 10081 and 10082.

Product # Description 100 mg 1000 mg
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10011 Phthalimidooxy-dPEG 4 NHS ester $100 $750

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Mol. Wt.: 508.48; single compound; dPEG Spacer is 17 atoms and 19.0 Å
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11135 Phthalimidooxy-dPEG 12 NHS ester $250 $1250

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Mol. Wt.: 860.90; single compound; dPEG Spacer is 41 atoms and 46.3 Å
References:
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Greg T. Hermanson, Bioconjugate Techniques, 3 Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See chapter 18, Discrete PEG Reagents, pp.787-821, for a full
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overview of the dPEG products.
Products Protected under U.S. Patents # 7,888,536 & 8,637,711

For custom synthesis please contact us at info@quantabiodesign.com 58