Page 17 - PC 101 practical notes 24-25..
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MANSOURA NATIONAL UNIVERSIY
         PHARM D- CLINICAL PHARMACY                        LEVEL I                        PHARM. ANAL. CHEM. I (PC 101)



          2. Phenolphthalein (ph.ph.):

               •  pH range ≈ (8.5 – 10) approximately.

               •  We use 10 drops of it in our experiments.


               •  Color:
                                               Colorless                     *                 Pink


                         pH   0                                     8.5            10                       14
                                                                                               
                                                 Acidic                    E.P.                Basic

                                               to ph.ph.                                   to ph.ph.

               *Color of ph.ph. at E.P.:

               -If the solution before starting titration is Colorless (i.e. acidic to ph.ph.)

                  E.P. is First Pink Color persistent for 30 seconds.

               -If  the  solution  before  starting  titration  is  Pink  (i.e.  basic  to

                 ph.ph.)  E.P. is First Colorless.



             Remember:
          
             ph.ph. (small letters) is phenolphthalein indicator
             while

                                                                                                 +
             pH (p small, H capital) is a measure of acidity or alkalinity { = –log [H ] }


           Question: Complete the following:

             Color of M.O. in water is yellow while color of ph.ph. in water is colorless.


          Example of acid-base reactions:

                                         NaOH  +  HCl  →  NaCl  +  H 2O
                                         (basic)     (acidic)    (neutral {pH=7})















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