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SVMIC Risk Basics: Systems
the “same dose” of medication rather than specifically asking him
how much he was on. The office notes for these visits indicated he
was taking Amiodarone 200mg two times per day instead of the
actual dose of 400mg three times per day. The patient’s symptoms
worsened, and he experienced an increase in weakness, dizziness,
and gait instability, so carotid studies and liver function tests
were performed, but follow-up of the lab results was not done.
Two months later, which was now four months after the patient’s
discharge, the patient’s nephrologist identified the discrepancy in
the patient’s medication record and the abnormally high dose of
amiodarone that was on the patient’s medication bottle brought
into that visit.
The nephrologist phoned the cardiologist to verify that the patient
should be on this much medication. The cardiologist told the
nephrologist to have the patient immediately discontinue the
medication. A few weeks later, the patient was admitted with
ongoing symptoms of weakness, dizziness, and gait instability. He
suffered a stroke, pneumonitis, and polyneuropathy and expired
one month later due to the effects of the toxicity.
How did this happen to a patient when there is a recognized protocol
for drugs such amiodarone? First, the discharging physician prescribed
the medication without calling to discuss the discharge needs of the
patient with the treating cardiologist who ordered the amiodarone. In
addition to that, he also failed to acknowledge his unfamiliarity with the
medication and contact someone, such as the hospital pharmacist, who
could provide guidance on the appropriate dosing strategy prior to giving
the patient a prescription for discharge. Following the patient’s discharge,
the cardiologist received a copy of the hospital discharge summary. This
discharge summary identified the dose of amiodarone that the patient
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