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SVMIC Risk Basics: Systems


                 the “same dose” of medication rather than specifically asking him

                 how much he was on. The office notes for these visits indicated he
                 was taking Amiodarone 200mg two times per day instead of the

                 actual dose of 400mg three times per day. The patient’s symptoms
                 worsened, and he experienced an increase in weakness, dizziness,

                 and gait instability, so carotid studies and liver function tests
                 were performed, but follow-up of the lab results was not done.

                 Two months later, which was now four months after the patient’s
                 discharge, the patient’s nephrologist identified the discrepancy in

                 the patient’s medication record and the abnormally high dose of
                 amiodarone that was on the patient’s medication bottle brought

                 into that visit.



                 The nephrologist phoned the cardiologist to verify that the patient
                 should be on this much medication. The cardiologist told the

                 nephrologist to have the patient immediately discontinue the
                 medication. A few weeks later, the patient was admitted with

                 ongoing symptoms of weakness, dizziness, and gait instability. He
                 suffered a stroke, pneumonitis, and polyneuropathy and expired

                 one month later due to the effects of the toxicity.







            How did this happen to a patient when there is a recognized protocol

            for drugs such amiodarone? First, the discharging physician prescribed
            the medication without calling to discuss the discharge needs of the

            patient with the treating cardiologist who ordered the amiodarone. In
            addition to that, he also failed to acknowledge his unfamiliarity with the

            medication and contact someone, such as the hospital pharmacist, who
            could provide guidance on the appropriate dosing strategy prior to giving

            the patient a prescription for discharge. Following the patient’s discharge,
            the cardiologist received a copy of the hospital discharge summary. This

            discharge summary identified the dose of amiodarone that the patient


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