Page 165 - Binder2
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nanoparticle system that can be adapted to multiple
               diseases.

               This allows COUR to:


                   •  De-risk clinical development by spreading
                       immune-tolerance proof points across
                       indications
                   •  Build partner-driven capital strategies instead of
                       relying solely on dilutive equity
                   •  Retain internal focus on R&D and platform
                       optimization, while partners handle downstream
                       commercial execution

               It’s a model that supports long-term scientific
               consistency—even if individual products succeed at
               different speeds.




               2. Strategic Partnerships Instead of Massive
               Infrastructure


               COUR avoids the overhead-heavy, vertically integrated
               model common in large pharma.
               Instead, it licenses or co-develops specific disease
               applications of its platform to bigger players—like
               Takeda, which partnered with COUR on its celiac disease
               program.

               This structure:

                   •  Brings in non-dilutive capital through upfront
                       payments, milestones, and royalties
                   •  Allows COUR to stay lean and focused on
                       platform innovation, not global commercialization

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