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If a leaf of engineered lettuce can deliver a microgram of
antigen that prevents a year of flares, that’s not low yield.

That’s high impact.

What We Need to Measure Instead

The future of biologics demands a new vocabulary around
yield—one that values:

• Durability per dose
• Tolerance induction per milligram
• Reduction in immune rejection events per
kilogram of biomass

This isn’t about abandoning productivity. It’s about
recalibrating what we call “productive.”

Because when you measure success by grams, you chase
volume.
But when you measure success by trust—by how long a
therapy continues to work—you design a very different
system.

One that may yield less up front.
But delivers more where it counts.

Glycosylation

Every biologic drug is a protein. But not every protein is
just a string of amino acids. Many are post-translationally

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