Page 171 - AAOMP Onsite Booklet

2018 Joint IAOP - AAOMP Meeting

#143 LUNG CARCINOMA METASTASIS TO THE MAXILLA AFTER
RECURRENT IMPLANTS FAILURE

Monday, 25th June - 00:00 - Poster Session Available from 25th (16:30- 18:30) -26th (18:30-20:30) June 2018 -
Bayshore Ballroom D-F - Poster - Abstract ID: 291

Dr. saverio capodiferro (University of bari), Prof. Gianfranco Favia (University of bari), Dr. Angela Tempesta (University of bari),
Dr. Roberto Maffei (Private dental practice), Dr. luisa Limongelli (University of bari), Prof. Anna Napoli (University of bari), Prof.
Eugenio Maiorano (University of bari)

Metastatic tumours involving the oro-facial tissues are infrequent, with an incidence ranging between 1-8% of oral
th
malignant tumours. The peak incidence is in the 5-7 decades and they can be the first sign of an occult cancer or
manifest during the follow-up of a patient with a known primary tumour.
We describe a case of metastasis from unknown lung adenocarcinoma occurring in the maxilla, around dental
implants, causing recurrent implants failure. A 62 year-old male without relevant clinical history was referred
for dental implant failure in the left maxilla. New dental implants were positioned in the same maxillary area,
but an additional implant failure occurred one month later; implants removal with an accurate bone curettage
was performed and the surgical sample sent for histological examination. Unexpectedly, small foci of adenocarci-
noma were found, with spiculae of medullary bone, prominent inflammatory changes and bacterial deposits. At
immunohistochemistry, the tumour positively stained for CK7+ and TTF1+ but not for CK20 and PSA. Additional
clinico-radiological investigations revealed a primary tumour of the lung, subsequently characterized as acinar
adenocarcinoma.
Metastases to the oro-facial tissues can involve the oral mucosa, jawbones and salivary glands; lung, kidney, prostate
and colon-rectum in males, uterus, breast, ovary and lungs in females are the most frequent primary localisations. It
is accepted that metastatic neoplasms in the oro-facial region show high predilection for sites with peculiar clinical
conditions, such as the parodontal inflammation or edentulous individuals bearing prosthesis.
The molar and premolar regions of the jawbones and the post-extraction sites frequently are involved; this was
related to the rich vascularisation and high bone marrow content and /or to re-organisation of the blood cloth of
such sites. This report highlights the importance of histological examination of gingival-parodontal inflamed tissues
when plaque and calculus accumulations have been excluded as primary causes.

145