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AFP decline, n (%) 11 (64.7) 4 (80) 7 (58.3) 0.380
irAE 2 (9.1) 2 (25) 0 0.036
Statistics presented as median (range), mean ± standard deviation or number
(percent).
# Recent R/T is defined as the interval between R/T and Nivolumab treatment
less than one month or concurrent.
AFP decline is defined as 10 % reduction of AFP after 2 months of Nivolumab
treatment.
Abbreviations: R/T, radiation therapy; HBV, hepatitis B virus; HCV, hepatitis C
virus; NA, not applicable; ALBI, albumin-bilirubin; MVI, macrovascular invasion;
EHS, extra-hepatic spread; AFP, alpha-fetoprotein; SBRT, stereotactic body
radiation therapy; OS, overall survival; PFS, progression-free survival; CR,
complete remission; PR, partial remission; SD, stable disease; PD, disease
progression; DCR, disease control rate; irAE, immune-related adverse event.
