Page 184 - YORAM RUDY BOOK FINAL

P. 184
69. Smith PL, Baukrowitz T, Yellen G. The inward rectification mechanism of the HERG cardiac

potassium channel. Nature. 1996 Feb 29;379(6568):833-6. doi: 10.1038/379833a0. PMID: 8587608.

70. Kiehn J, Lacerda AE, Brown AM. Pathways of HERG inactivation. Am J Physiol.
1999 Jul;277(1):H199-210. doi: 10.1152/ajpheart.1999.277.1.H199. PMID: 10409198.

71. Clancy CE, Rudy Y. Cellular consequences of HERG mutations in the long QT syndrome:
precursors to sudden cardiac death. Cardiovasc Res. 2001 May;50(2):301-13. doi: 10.1016/s0008-
6363(00)00293-5. PMID: 11334834.

72. Silva J, Rudy Y. Subunit interaction determines I participation in cardiac repolarization
Ks
and repolarization reserve. Circulation. 2005 Sep 6;112(10):1384-91. doi: 10.1161/CIRCULATIONA-
HA.105.543306. Epub 2005 Aug 29. Erratum in: Circulation. 2009 Sep 8;120(10):e84. PMID: 16129795;

PMCID: PMC1820744.

73. Wang Q, Curran ME, Splawski I, Burn TC, Millholland JM, VanRaay TJ, Shen J, Timothy KW,
Vincent GM, de Jager T, Schwartz PJ, Toubin JA, Moss AJ, Atkinson DL, Landes GM, Connors TD,

Keating MT. Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause
cardiac arrhythmias. Nat Genet. 1996 Jan;12(1):17-23. doi: 10.1038/ng0196-17. PMID: 8528244.

74. Splawski I, Tristani-Firouzi M, Lehmann MH, Sanguinetti MC, Keating MT. Mutations in the

hminK gene cause long QT syndrome and suppress I function. Nat Genet. 1997 Nov;17(3):338-40.
Ks
doi: 10.1038/ng1197-338. PMID: 9354802.

75. Chen H, Kim LA, Rajan S, Xu S, Goldstein SA. Charybdotoxin binding in the I pore
Ks
demonstrates two MinK subunits in each channel complex. Neuron. 2003 Sep 25;40(1):15-23.
doi: 10.1016/s0896-6273(03)00570-1. PMID: 14527430.

76. Pusch M. Increase of the single-channel conductance of KvLQT1 potassium channels

induced by the association with minK. Pflugers Arch. 1998 Dec;437(1):172-4. doi: 10.1007/
s004240050765. PMID: 9817805.

77. Sesti F, Goldstein SA. Single-channel characteristics of wild-type IKs channels and channels

formed with two minK mutants that cause long QT syndrome. J Gen Physiol. 1998 Dec;112(6):
651-63. doi: 10.1085/jgp.112.6.651. PMID: 9834138; PMCID: PMC2229448.

78. Yang Y, Sigworth FJ. Single-channel properties of I potassium channels. J Gen Physiol.
Ks
1998 Dec;112(6):665-78. doi: 10.1085/jgp.112.6.665. Erratum in: J Gen Physiol 1999 Mar;113(3):505.
PMID: 9834139; PMCID: PMC2229447.