Page 90 - YORAM RUDY BOOK FINAL

P. 90

Figure 3.10. Conduction velocity (A) and SF (B) with reduced excitability (dashed line) or reduced
intercellular coupling (solid line). Minimum velocity attainable before conduction block is about
1/200 of control with reduced coupling, while it is only 1/3 of control with reduced excitability
(conduction block is indicated by asterisk). Although both reduced excitability and reduced
coupling slow propagation, reduced excitability decreases SF, whereas decreased coupling
increases SF. For this reason, reduced coupling can support much slower conduction. From
Shaw and Rudy [174], with permission from Wolters Kluwer Health, Inc.