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A28    SCIENCE
              Tuesday 20 February 2018
            Medical examiner taps DNA science to find missing persons




            By VERENA DOBNIK                                                                                                    Unidentified  Persons  Sys-
            NEW YORK (AP) — For fami-                                                                                           tem. The system is capable
            lies  who  have  searched                                                                                           of searching for unique sim-
            years  for  missing  loved                                                                                          ilarities  in  DNA  strings  that
            ones,  donating  a  sample                                                                                          indicate  two  people  are
            of their DNA is often a last,                                                                                       related.
            desperate  act  to  confirm                                                                                         "Our  job  is  to  help  identify
            their worst fears.                                                                                                  your loved one and return
            New York City's medical ex-                                                                                         them  to  you,  no  matter
            aminer is leading a nation-                                                                                         where in the United States.
            wide  effort  to  collect  ge-                                                                                      They  don't  have  to  have
            netic  material  and  match                                                                                         died here in New York City,"
            it  with  unidentified  human                                                                                       says  Mark  Desire,  assistant
            remains. It's a way to finally                                                                                      director of the medical ex-
            give family members some                                                                                            aminer's Department of Fo-
            answers and maybe some                                                                                              rensic Biology.
            solace.                                                                                                             Mary  Lyall  submitted  her
            "People  will  not  rest  with-                                                                                     DNA  to  the  New  York  City
            out answers, at least some                                                                                          medical  examiner,  along
            answers,"  said  Dr.  Barbara                                                                                       with her husband's, as part
            Sampson,  the  city's  chief                                                                                        of  her  hunt  for  her  missing
            medical examiner.                                                                                                   daughter.
            Over the last decade, thou-   In this June 4, 2010 file photo, a criminalist examines for DNA evidence at a lab in the NYC Office   Suzy  Lyall  was  19  when
            sands of DNA samples have    of Chief Medical Examiner, Friday, June 4, 2010, in New York.                          she  disappeared  in  1998.
            been donated to the city's                                                                         Associated Press  She  was  last  seen  on  the
            medical  examiner's  office.                                                                                        University  at  Albany  cam-
            Most  include  swabs  of  sa-  and  crossed  the  U.S.  bor-  One such advance, Samp-  Pulverized genetic material  pus getting off a bus. After
            liva from close relatives, but  der  from  Mexico.  DNA  son said, was learning how  is spun in a centrifuge and  she  vanished,  her  mother
            also DNA taken from items  matched  with  the  remains  to get good genetic mate-      turned  into  a  clear  liquid  sifted through her room at
            used  by  the  missing  per-  of a 35-year-old "John Doe"  rial out of bone fragments.  that's poured into test tubes  home  looking  for  clues.  In
            sons  themselves,  including  who  succumbed  to  expo-   DNA testing once required  on a robotic assembly line.  a  wastebasket,  she  found
            toothbrushes, combs, razor  sure and dehydration in the  a large sample of blood or  The  tubes  are  bar-coded  a sanitary napkin Suzy had
            blades and, once, even a  Texas desert.                   saliva  that  was  often  de-  and  padlocked  in  metal  wrapped  and  discarded
            sanitary napkin.             "It's sad," Merchan said. "We  stroyed in the process. The  cages in a secure vault.   amid crumpled paper. Two
            They've  led  to  the  identi-  hoped  Manuel  would  call  latest  genetic  technology  Genetic profiles developed  decades  later,  no  match
            fication  of  about  50  miss-  one  day.  But  we  at  least  allows  a  few  cells  to  be  from the tests are plugged  has been made. "I still look
            ing  people  each  year,  all  know what happened."       reproduced  for  DNA  that  into  the  databank  called  out the window and think,
            of  whom  had  been  found  On  any  given  day,  there  lasts indefinitely.           the  National  Missing  and  'Where is she?'" Lyall said.q
            dead.  But  for  many  who  are as many as 100,000 ac-
                                         in  the  U.S.,  according  to  Experts: Underwater archaeology
            have  submitted  samples,  tive  missing-persons  cases
            the wait continues.
            "Part  of  you  hopes  they  the FBI's National Crime In-
            never  call  you,  because  formation  Center.  Most  of   site imperiled in Mexico
            if  they  call,  that  means  it's  those people are eventual-
            over," said Rose Cobo, who  ly found safe. The medical
            submitted DNA to the pro-    examiner's  office  program   MEXICO  CITY  (AP)  —  Pol-  the  continent  have  been  gest water levels may have
            gram after her adult niece  is  open  to  people  whose   lution  is  threatening  the  found  there,  dating  back  briefly dropped in the 216-
            vanished  in  2016  after  be-  loved  ones  have  been   recently  mapped  Sac  Ac-   more  than  12,000  years,  mile  (347-kilometer)  -long
            ing  treated  at  a  Brooklyn  missing 60 days or more.   tun cave system in the Yu-   and  now-extinct  animal  system  during  a  drought
            hospital for postpartum de-  The New York City medical    catan  Peninsula,  a  vast  remains  push  the  horizon  about 1,000 A.D. And some
            pression following the birth  examiner's office has been   underground  network  that  back  to  15,000  years.  He  artifacts  have  been  found
            of  a  son.  Chelsea  Cobo's  a  pioneer  in  advanced    experts in Mexico say could  said  researchers  found  a  dating  to  the  1847-1901
            whereabouts  are  still  un-  DNA techniques since 9/11,   be the most important un-   human  skull  that  was  al-  Maya  uprising  known  as
            known.                       when  it  was  tasked  with   derwater  archaeological  ready covered in rainwater  the War of the Castes.
            The  program  helped  end  using  genetic  evidence       site in the world. Subaquat-  limestone deposits long be-  Humans  there  probably
            Luis  Merchan's  quest  to  to identify and sort tens of   ic  archaeologist  Guillermo  fore the cave system flood-  didn’t live in the caves, de
            find  his  younger  brother,  thousands  of  small  pieces   de Anda said the cave sys-  ed around 9,000 years ago.  Anda said, but rather went
            Manuel,  who  was  report-   of  human  remains  found    tem’s historical span is like-  De Anda said over 120 sites  down  to  them  “during
            ed  missing  in  2015  after  in  the  rubble  of  the  World   ly  unrivaled.  Some  of  the  with Maya-era pottery and  periods  of  great  climate
            he  left  his  native  Ecuador  Trade Center.             oldest  human  remains  on  bones  in  the  caves  sug-   stress,  to  look  for  water.”
                                                                                                                                Sac Actun is “probably the
                                                                                                                                most  important  underwa-
                                                                                                                                ter  archaeological  site  in
                                                                                                                                the world,” he said. But de
                                                                                                                                Anda  said  pollution  and
                                                                                                                                development  may  threat-
                                                                                                                                en  the  caves’  crystalline
                                                                                                                                water. Some of the sinkhole
                                                                                                                                lakes  that  today  serve  as
                                                                                                                                entrances to the cave sys-
                                                                                                                                tem are used by tourists to
                                                                                                                                snorkel and swim. q
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