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SCIENCESaturday 20 January 2018

Gov't scientists scramble to save research ahead of shutdown

By LAURAN NEERGAARD           Dr. Anthony Fauci of the National Institutes of Health speaks dur-                      "You have experiments          attempts, the hurdles to
AP Medical Writer             ing an AP Newsmaker interview in Washington, Thursday, Jan.                             that have been going on        getting an HIV vaccine
WASHINGTON (AP) — The         18, 2018.                                                                               for months if not years, and   are "surmountable," but ex-
nation's premier medical                                                                                              then all of a sudden you've    pect such a shot to be only
research institute is in "a                                                                       Associated Press    got to stop — you can't do     partially effective. Even
scramble" to prepare for                                                                                              that," Fauci said. "You can't  a vaccine that's 50 to 60
a partial government shut-    described how researchers                               tial shutdown — and who         push the pause button on       percent effective "would
down that could ruin costly   working on projects from                                would be barred. There's        an experiment when you         be a home run" because
experiments and leave sick    cancer therapies to new                                 also a potential ripple ef-     inject an animal with a        it could be combined
patients unable to enter      vaccines are figuring out                               fect, because NIH funds         particular substance to see    with condoms, preventive
cutting-edge studies, Dr.     how to try to save work in                              basic research and clini-       what the response is and       medications and other
Anthony Fauci of the Na-      progress so it wouldn't go                              cal trials at universities and  then you have to go home       steps, Fauci said.
tional Institutes of Health   to waste.                                               other institutions across the   for a week."                   "When you put even a
said Thursday.                "It's a scramble," Fauci                                country.                        In a wide-ranging interview    modestly effective HIV
Fauci stressed that patients  said, offering a peek at                                Fauci, who directs the Na-      Thursday, Fauci also said:     vaccine together with all
currently in NIH-run stud-    the practical impact of the                             tional Institute of Allergy     — It's too soon to know        of the other prevention
ies — including those at      budget impasse.                                         and Infectious Diseases,        how well this year's flu vac-  modalities, I think we could
the research-only hospital    As at other federal agen-                               called the cycle of off-        cine is protecting against     put an end to the epidem-
often called the "house       cies, NIH must determine                                and-on budget deals and         the tough virus strain hit-    ic. That's what I hope we
of hope" — wouldn't be        who is an "essential" em-                               shutdown threats demoral-       ting much of the country.      can do at least while I'm
adversely affected even       ployee and would report                                 izing and disruptive to sci-    Probably the flu shot will be  still alive," he said.
if President Donald Trump     to work if there is a par-                              ence.                           about 30 percent effec-        —Science has the capabil-
and Congress don't reach                                                                                              tive, he estimated, and he     ity, given the right resourc-
a budget deal to avert a                                                                                              said science must come         es, to create vaccines for
shutdown at midnight Fri-                                                                                             up with better protection      tuberculosis and malaria,
day. "We still take care of                                                                                           against the constantly mu-     as well as HIV. Tackling all
them," Fauci, the NIH's in-                                                                                           tating virus.                  three, "you're talking about
fectious disease chief, told                                                                                          He is prioritizing develop-    millions and millions of lives
The Associated Press. "You                                                                                            ment of a universal flu vac-   per year that you'll be sav-
never want to put patients                                                                                            cine to protect against        ing." —Zika may have fad-
in any jeopardy."                                                                                                     both seasonal flu and su-      ed from the headlines but
But new patients attempt-                                                                                             per-strains that can trigger   if it rebounds in Latin Amer-
ing to enter studies of ex-                                                                                           pandemics. How soon?           ica, NIH has "a vaccine
perimental therapies, of-                                                                                             "Years, not decades," he       ready to go and prove
ten because they've failed                                                                                            said. Meanwhile, get the       whether it's effective or
standard treatment, would                                                                                             regular flu vaccine: "Any      not." Perhaps more impor-
have to be turned away,                                                                                               degree of protection is        tant, it was made in a way
as happened during the                                                                                                better than no protection      that NIH thinks could be
last government shutdown.                                                                                             at all."                       copied quickly to fend off
And across the NIH, Fauci                                                                                             —Despite years of failed       other emerging viruses.q

                                                                                      Expert says major eruption in
                                                                                      Papua New Guinea could be soon

In this photo taken on Tuesday, Jan. 16, 2018, ash plumes rise                        CANBERRA, Australia (AP)        recently increased be-         two boats to completely
from the volcano on Kadovar Island, Papua New Guinea in the                           — Seismic activity beneath      neath the volcano.             evacuate the 600 Kadovar
South Pacific.                                                                        a Papua New Guinea vol-         "The reason we're getting      residents to the mainland.
                                                                                      cano could mean that a          activity is probably be-       He could not say whether
                                                                    Associated Press  major eruption was immi-        cause new magma is mov-        the evacuations of nearby
                                                                                      nent, a scientist said Thurs-   ing up from deeper down,"      islands had been complet-
                                                                                      day.                            Saunders told Australian       ed by Thursday.
                                                                                      Thousands of people have        Broadcasting Corp.             Papua New Guinea sits on
                                                                                      been evacuated from is-         Prime Minister Peter O'Neill   the "Ring of Fire," a line of
                                                                                      lands surrounding Kadovar       has said state resources       seismic faults encircling the
                                                                                      Island off the South Pacific    were being made avail-         Pacific that has frequent
                                                                                      nation's north coast since      able to support evacua-        earthquakes and volcanic
                                                                                      a volcano there began           tions and he warned north-     eruptions.q
                                                                                      erupting on Jan. 5, spout-      ern coastal communities to
                                                                                      ing ash. Flights nearby         be alert for possible tsuna-
                                                                                      have been canceled due          mis. Kadovar is offshore to
                                                                                      to the risk posed by ash        the north of New Guinea,
                                                                                      plumes and ships were           the larger island that in-
                                                                                      warned to stay away from        cludes Papua New Guin-
                                                                                      the island.                     ea's capital, Port Moresby.
                                                                                      Steve Saunders, principal       Aikari Muri, the Internation-
                                                                                      geodetic surveyor at the        al Red Cross' disaster risk
                                                                                      Rabaul Volcano Observa-         management logistics offi-
                                                                                      tory in Papua New Guinea,       cer for Papua New Guinea,
                                                                                      said seismic activity had       said the military had used
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