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A12   SCIENCE
                   Monday 5 october 2020

            Nobel Prizes and COVID-19: Slow, basic science may pay off



            By SETH BORENSTEIN                                                                                                  als. Airplanes are designed
            AP Science Writer                                                                                                   at  the  very  edge  of  what
            While  the  world  wants                                                                                            is  possible.  Even  cars  are
            flashy quick fixes for every-                                                                                       completely  dependent  on
            thing,  especially  massive                                                                                         basic science.''
            threats like the coronavirus                                                                                        But  some  people  don't
            and  global  warming,  next                                                                                         make    that   connection.
            week's Nobel Prizes remind                                                                                          Adam  Riess,  who  won
            us that in science, slow and                                                                                        the  2011  Nobel  in  physics,
            steady pays off.                                                                                                    and  Tyson  said  this  is  es-
            It may soon do so again.                                                                                            pecially  noticeable  when
            Science  builds  upon  pre-                                                                                         people  who  deny  climate
            vious  work,  with  thinkers                                                                                        science  or  vaccine  effec-
            "standing  on  the  shoulders                                                                                       tiveness do so while reach-
            of  giants,"  as  Isaac  New-                                                                                       ing  fellow  nonbelievers  on
            ton put it, and it starts with                                                                                      smartphones  and  Google
            basic  research  aimed  at                                                                                          searches  made  possible
            understanding  a  problem                                                                                           because  of  basic  science
            before fixing it.                                                                                                   research.
            It's  that  type  of  basic  sci-                                                                                   "Maybe,  maybe  science
            ence  that  the  Nobels  usu-                                                                                       needs  a  PR  agent,  OK?"
            ally  reward,  often  years  or                                                                                     Tyson  said  in  an  interview.
            decades after a discovery,   In this April 17, 2015, file photo, a national library employee shows a gold Nobel Prize medal in   "Maybe with a new discov-
            because  it  can  take  that   Bogota, Colombia.                                                                    ery in science in a way that
            long to realize the implica-                                                                       Associated Press  affects your life outcomes,
            tions.                                                                                                              the  TV  commercials  say,
            Slow  and  steady  success  of Sciences.                  ies  from  20  years  ago  are  of the Hayden Planetarium.  'Did  you  know  this?  This
            in  science  has  made  re-  The  coronavirus  was  se-   going  to  be  key  to  treat-  How  about  seeing  bet-  thing that you're using was
            searchers  hopeful  in  the  quenced  in  a  matter  of  ing  and  preventing  CO-     ter,  without  glasses,  thanks  invented  here  in  this  lab
            fight  against  the  pandem-  weeks,  testing  became  VID  next  year,"  said  Sudip  to  LASIK  surgery?  That  by  this  person.  And  it  was
            ic. It even offers a glimmer  available quickly, and vac-  Parikh,  CEO  of  the  Ameri-  stemmed  from  research  brought  to  market  by  this
            of climate optimism.         cines  that  would  normally  can  Association  for  the  into  precise  lasers  that  led  company. And now you're
            Many  years  of  advances  take  years  may  be  devel-   Advancement  of  Science.  to the 2018 Nobel for phys-    using  it  and  enjoying  it.'
            in  basic  molecular  sci-   oped in a year or less, and  "That was made possible by  ics, but was also the prod-   Stop in silence. 'You're wel-
            ence,  some  of  them  al-   "it's  all  been  built  on  the  basic research.''       uct of an accident in which  come.'"
            ready  Nobel  Prize-winning,  back of basic science ad-   Basic  research  comes  first.  a researcher got lasered in  As   for   fixing   climate
            have given the world tools  vances that have been de-     The  benefits  are  typically  the eye, said microbiologist  change,  Mexican  chem-
            for  fast  virus  identification  veloped  in  the  past  three  reaped only later, in what is  Rita  Colwell,  former  head  ist Mario Molina  has hope
            and  speeded  up  the  de-   decades," McNutt said.       called applied science.      of the U.S. National Science  that the world will be able
            velopment  of  testing.  And  She  pointed  to  gene  se-  "Without basic science, you  Foundation.                 to  solve  the  problem  be-
            now  they  tantalize  us  with  quencing  and  polymerase  won't  have  cutting-edge  And those lasers used con-    cause of the work that led
            the  prospect  of  COVID-19  chain  reaction,  which  al-  applied   science,"   said  cepts  that  date  back  to  to his 1995 Nobel Prize.
            treatments  and  ultimately  lows  for  multiple  copying  Frances  Arnold,  a  Caltech  Albert  Einstein,  said  British  He  and  others  discovered
            a  vaccine,  perhaps  within  of  precise  DNA  segments.  chemical  engineer  who  Royal  Astronomer  Martin  that  industrial  chemicals
            a few months.                That  latter  discovery  won  won  the  2018  Nobel  in  Rees.                         known  as  chlorofluorocar-
            "This could be science's fin-  the  1993  Nobel  in  chemis-  chemistry.               John Mather, who won the  bons  were  reaching  high
            est hour. This could be the  try.                         Nobel-winning  basic  re-    2006 physics Nobel for cos-  into  the  atmosphere  and
            time  when  we  deliver,  not  And  even  further  back,  in  search  has  allowed  us  to  mology, which is the study  eating away at Earth's pro-
            just  for  the  nation  but  the  1984, the Nobel in medicine  see  the  world  in  a  whole  of the origin of the universe  tective ozone layer. He dis-
            world, the miracle that will  went  to  a  team  for  theo-  new light.                and is thus the ultimate ba-  covered  this  many  years
            save  us,"  said  geophysicist  ries  on  how  to  manipulate  Do you like white, efficient  sic science, said nearly ev-  before  an  ozone  hole  de-
            Marcia  McNutt,  president  the  immune  system  using  LED  light  to  replace  the  erything we use around us  veloped over Antarctica.
            of  the  National  Academy  something  called  mono-      nasty  fluorescent  hum  of  is  there  because  of  basic  His  work  and  the  opening
                                         clonal   antibodies.   Now  industrial  lighting  or  ener-  science.                  of  the  hole  led  to  a  1987
                                         those antibodies are one of  gy-gobbling  incandescent  "Engineers  and  entrepre-     international agreement to
                                         the best hopes for a treat-  bulbs? A key part of those  neurs  use  this  knowledge  ban those ozone-depleting
                                         ment for the coronavirus.    lights are blue light-emitting  to  build  commercial  em-  chemicals,  and  the  hole
                                         "Despite  the  politics,  de-  diodes,  and  their  discov-  pires," he said. "Doctors use  has  started  shrinking.  Now
                                         spite whatever other things  ery won the 2014 Nobel in  what  we  find  to  develop  Molina  hopes  that  kind  of
                                         are  slowing  us  down,  No-  physics,  said  astrophysicist  new cures. Architects build  action  can  be  applied  to
                                         bel  Prize-winning  discover-  Neil  deGrasse  Tyson,  head  houses with modern materi-  what  he  calls  "the  climate
                                                                                                                                emergency."
                                                                                                                                "That's  why  I'm  optimistic.
                                                                                                                                Because  we  do  have  one
                                                                                                                                example of a global prob-
                                                                                                                                lem  where  practically  all
                                                                                                                                the countries of the planet
                                                                                                                                agreed  to  work  together.
                                                                                                                                The ozone layer is healing. It
                                                                                                                                takes quite awhile," Molina
                                                                                                                                said. "But it's working, slowly.
                                                                                                                                So it can be done."q
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