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Management of Systemic Lupus Erythematosus

                             TABLE OF CONTENTS

           No.  Title                                          Page
           9.  MONITORING                                        30
               9.1  Clinical Features                            30
               9.2  Laboratory Investigations                    30
               9.3  Co-morbidities                               31
               9.4  Drug Adverse Events                          33
               9.5  Frequency and Interval                       34
           10.  SPECIAL CONSIDERATION                            35
               10.1  Antiphospholipid Syndrome                   35
               10.2  Pregnancy                                   36
               10.3  Lactation                                   40
               10.4  Adolescents                                 40
               10.5  Vaccination                                 41

           11.  REFERRAL                                         43

           12.  IMPLEMENTING THE GUIDELINES                      44
               12.1  Facilitating and Limiting Factors           44
               12.2  Potential Resource Implication              44

               REFERENCES                                        46

               Appendix 1  Example of Search Strategy            54
               Appendix 2  Clinical Questions                    55
               Appendix 3  2012 SLICC Classification Criteria for SLE   57
               Appendix 4  2019 EULAR/ACR Classification Criteria    59
                          for SLE
               Appendix 5  Systemic Lupus Erythematosus Disease    60
                          Activity Index - 2000 (SLEDAI-2K)
               Appendix 6  British Isles Lupus Activity Group (BILAG)    62
                          Index - 2004
               Appendix 7  Medication in SLE                     64
               Appendix 8  Frequency of Monitoring Patients with SLE   70
               Appendix 9  Sapporo Classification Criteria       72
               Appendix 10  Recommendations on Types of          74
                          Contraception for Patients with SLE

               List of Abbreviations                             79
               Acknowledgement                                   79
               Disclosure Statement                              79
               Source of Funding                                 79
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