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Concepts in Veterinary Toxicology Chapter | 1 5
VetBooks.ir half of the book indicating the importance of poisonous ogy as part of the National Veterinary Medical Series for
Osweiler (1996) has authored a text focused on toxicol-
plants in that era of veterinary medicine.
Many early students in veterinary medicine in the
Independent Study. It has been widely used by individuals
United States used textbooks prepared for physicians such preparing for the National Board Examinations for
as Kobert (1897), Practical Toxicology for Physicians Veterinary Medical Licensing. Roder (2001) has prepared a
and Students. It was also common to use either textbooks text, Veterinary Toxicology,aspartofaseries, The Practical
in pharmacology or veterinary pharmacology that con- Veterinarian. This was followed by a version edited by
tained a brief coverage of toxicology. Indeed, few veteri- Chapman and Campbell, 2011. More recently, two updates
nary medical colleges prior to the 1950s had full-time have been released: Blackwell’s Five-Minute Veterinary
veterinary toxicologists on their faculty. Lectures on toxi- Consult Clinics Companion: Small Animal Toxicology
cology were usually included in courses in pharmacology, (Hovda et al., 2016) and Canine and Feline (Tilley and
pathology, and clinical medicine. Smith, 2015). Plumlee (2004) has edited Clinical Veterinary
The first veterinary toxicology text I personally used Toxicology, and Peterson and Talcott have edited three edi-
wasauthoredbyR.John Garner (1957) who was then a tions of Small Animal Toxicology, the most recent edited of
Senior Lecturer in Chemical Pathology (Veterinary) at the whichwas publishedin2012(Peterson and Talcott, 2012).
University of Bristol in the United Kingdom and later Head Small Animal Toxicology Essentials, first edition, by
of the Radiobiology Department at the Agricultural Poppenga and Gwaltney-Brant (2011) is also a valuable
Research Council Field Station, Compton, Berks, United reference. In my opinion, the present multiauthored text edi-
Kingdom. At the Compton Station he conducted pioneering ted by Ramesh Gupta is the most comprehensive text on
research on the fate of important radionuclides in domestic veterinary toxicology published to date. It is encouraging that
animals. The text by Garner (1957) was intended as a suc- it is now appearing in a third edition.
cessor to the third edition of Lander’s Veterinary There are a number of comprehensive general toxicol-
Toxicology (Nicholson, 1945). A second edition was pre- ogy texts available today. I will note five that the serious
pared by Garner (1961) after he became head of the Public student of toxicology will find useful to have in their
Health Section, Radiological Protection Division, UK reference library. Casarett and Doull’s Toxicology: The
Atomic Energy Authority, Harwell, Berks, United Basic Science of Poisons edited most recently by
Kingdom. I visited Garner in 1962 and discussed with him Klaassen (2013) was first published in 1975 and is now in
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the release of I in the 1957 Windscale reactor accident. its eighth edition. As an aside, I had the opportunity to
This accident emphasized the importance of the dairy cow observe first hand Louis Casarett and John Doull planning
milk pathway for human exposures. Later, Garner came to the first edition of this new textbook as I served with
the United States where he was initially associated with them on the Toxicology Study Section of the National
Colorado State University directing studies of the long-term Institute of Health. Unfortunately, Louis Casarett died of
effects of external radiation on Beagles. I recall asking cancer before the first edition (Casarett and Doull, 1975)
Garner in the early 1970s about the possibility of preparing was completed. I was pleased when John Doull asked me
a third edition of his veterinary toxicology text. He to prepare the chapter that Louis had intended to write on
responded that the field of veterinary toxicology had radiation toxicology, which I did with my colleague,
become so broad that it was not readily feasible for a single Charles Hobbs (Hobbs and McClellan, 1975). Hayes’
individual to author a text in veterinary toxicology and he Principles and Methods in Toxicology is now in its sixth
was not interested in “shepherding a herd of individual edition (Hayes and Kruger, 2014). Toxicology, edited by
chapter authors” with specialized knowledge of various Marquardt et al. (1999) is built on an earlier German text
aspects of veterinary toxicology. With this textbook, Gupta by Marquardt and Schafer (1994, 2004). Biological
has responded to the challenge offered by Garner. Concepts and Techniques in Toxicology: An Integrated
Radeleff (1964) authored one of the first veterinary toxi- Approach edited by Riviere (2006) is a concise textbook.
cology texts published in the United States. A second edi- Another pioneer in toxicology, Ernest Hodgeson, has edi-
tion appeared in 1970. This was followed by a text prepared ted a textbook that is now in its fourth edition (Hodgeson,
by Osweiler et al. (1985). Several books published in the 2010). Serious students will also want to be aware of
1960s became classics on the effects of poisonous plants a multivolume comprehensive set of toxicology text-
(Kingsbury, 1954, 1964; Hulbert and Oehme, 1968). Recent books. The first edition was edited by Sipes and collea-
books on poisonous plants have been authored by Garland gues (1997) a 14-volume second edition edited by
and Barr (1998), Burrows and Tyrl (2006),and Knight and McQueen (2010). Moreover, there are numerous text and
Walter (2001). Murphy (1996) has authored a field guide to reference books available now covering various subspe-
common animal poisons. It is organized by the organ sys- cialty areas such as inhalation toxicology, reproductive
tem affected and then by toxicant. and developmental toxicology, and dermal toxicology.