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Respiratory Acid-Base Disorders 299

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as nebulized furosemide, 56 opioids , corticosteroids, 61 12. Brunson DB, Hogan KJ. Malignant hyperthermia: a syn-
and application of chest wall vibration 10 have been drome not a disease. Vet Clin North Am Small Anim Pract
suggestedtorelievedyspneaandanyassociatedrespiratory 2004;34:1419–33.
13. Bureau M, Bouverot P. Blood and CSF acid-base changes
acid-base disturbances. In any case, the recognition of dys-
and rate of ventilatory acclimatization of awake dogs to
pnea in our veterinary patients as an abnormal, unpleasant 3,550 m. Respir Physiol 1975;24:203–16.
stimulus associated with respiratory abnormalities may 14. Caruana-Montaldo B, Gleeson K, Zwillich CW. The
alter our future medical management of disorders control of breathing in clinical practice. Chest
2000;117:205–25.
associated with respiratory acid-base abnormalities.
15. de Morais HAS, DiBartola SP. Ventilatory and metabolic
compensation in dogs with acid-base disturbances. J Vet
SUMMARY Emerg Crit Care 1991;1:39–49.
16. DiBartola SP, de Morais HAS. Respiratory acid-base
Respiratory acid-base disorders and derangements in arte- disorders. In: DiBartola SP, editor. Fluid therapy in small
animal practice. Philadelphia: WB Saunders; 1992.
rial blood gases are common entities that may lead to
p. 258–75.
increasedmorbidityandmortalityinsmallanimalpatients. 17. Epstein SK, Singh N. Respiratory acidosis. Respir Care
Early and proper diagnosis of these disease states is essen- 2001;46:366–83.
tial in providing correct and effective therapy. More wide- 18. Feldman JL. Neurophysiology of breathing in mammals.
spread availability of cost-effective, “bedside” portable In: Bloom FE, Mountcastle VB, editors. Handbook of
physiology. Section I, the nervous system, vol. 4, Intrinsic
blood gas analyzers in small animal practice allows the
regulatory systems of the brain. Bethesda: American
practitioner to monitor acid-base and oxygenation status Physiological Society; 1986. p. 463–524.
of the patient, thus providing more efficient, high quality 19. Feldman JL, Mitchell GS, Nattie EE. Breathing: rhythmic-
care for the compromised small animal patient. ity, plasticity, chemosensitivity. Annu Rev Neurosci
2003;26:239–66.
20. Galla JH, Luke RG. Chloride transport and disorders of
acid-base balance. Annu Rev Physiol 1988;50:141–58.
REFERENCES 21. Gandevia SC, Killian KJ, Campbell EJ. The effect of respi-
ratory muscle fatigue on respiratory sensations. Clin Sci
1. Adrogue ´ HJ, Madias NE. Management of life-threatening (Lond) 1981;60(4):463–6.
acid-base disorders (two parts). N Engl J Med 22. Gennari FJ, Goldstein MB, Schwartz WB. The nature of
1998;338:26–34. the renal adaptation to chronic hypocapnia. J Clin Invest
2. Adrogue ´ HJ, Madias NE. Changes in plasma potassium 1972;51:1722–30.
concentration during acute acid-base disturbances. Am J 23. Gennari FJ, Kassirer JP. Respiratory alkalosis. In: Cohen JJ,
Med 1981;71:456–67. Kassirer JP, editors. Acid-base. Boston: Little, Brown &
3. Alberti E, Hoyer S, Hamer J, et al. The effect of carbon Co.; 1982. p. 349–76.
dioxide on cerebral blood flow and cerebral metabolism 24. Giebisch G, Berger L, Pitts RF. The extrarenal response to
in dogs. Br J Anaesth 1975;47:941–7. acute acid-base disturbances of respiratory origin. J Clin
4. Alfaro V, Torras R, Iba ´n ˜ez J, et al. A physical-chemical Invest 1955;34:231–45.
analysis of the acid-base response to chronic obstructive 25. Gougoux A, Kaehny WD, Cohen JJ. Renal adaptation to
pulmonary disease. Can J Physiol Pharmacol chronic hypocapnia: dietary constraints to achieving H
1996;74:1229–35. {SY}þ{/SY} retention. Am J Physiol 1975;229:1330–7.
5. Arvidsson S, Haggendal E, Winso I. Influence on cerebral 26. Gray BA, Blalock JM. Interpretation of the alveolar-arterial
blood flow of infusion of sodium bicarbonate during respi- oxygen difference in patients with hypercapnia. Am Rev
ratory acidosis and alkalosis in the dog. Acta Anaesthesiol Respir Dis 1991;143:4–8.
Scand 1981;25:146–52. 27. Greene KE, Peters JI. Pathophysiology of acute respiratory
6. Ballantyne D, Scheid P. Central chemosensitivity of respira- failure. Clin Chest Med 1994;15:1–12.
tion: a brief overview. Respir Physiol 2001;129:5–12. 28. Hampson NB, Jo ¨bsis-VandlerVliet FF, Piantadosi CA.
7. Barnard P, Andronikou S, Pokorski M, et al. Time-depen- Skeletal muscle oxygen availability during respiratory
dent effect of hypoxia on carotid body chemosensory acid-base disturbances in cats. Respir Physiol
function. J Appl Physiol 1987;63:685–91. 1987;70:143–58.
8. Bateman SW. Ventilating the lung injured patient: what’s 29. Hara Y, Nezu Y, Harada Y, et al. Secondary chronic
new? In: Proceedings of the American College of Veterinary respiratory acidosis in a dog following the cervical cord
Surgeons Symposium. 2001. p. 562–5 Chicago. compression by an intradural glioma. J Vet Med Sci
9. Binks AP, Moosavi SH, Banzett RB, et al. Tightness” sen- 2002;64:863–6.
sation of asthma does not arise from the work of breathing. 30. Harrington JT, Kassirer JP. Metabolic alkalosis. In:
Am J Respir Crit Care Med 2002;165(1):78–82. Cohen JJ, Kassirer JP, editors. Acid-base. Boston: Little,
10. Bloch-Salisbury E, Binks AP, Banzett RB, et al. Mechanical Brown & Co.; 1982. p. 227–306.
chest-wall vibration does not relieve air hunger. Respir 31. Hodgkin JE, Soeprono FF, Chan DM. Incidence of
Physiol Neurobiol 2003;134(3):177–90. metabolic alkalemia in hospitalized patients. Crit Care
11. Brofman JD, Leff AR, Munoz NM, et al. Sympathetic Med 1980;8:725–8.
secretory response to hypercapnic acidosis in swine. J Appl 32. Ho ¨hne C, Boemke W, Schleyer N, et al. Low sodium intake
Physiol 1990;69:710–7. does not impair renal compensation of hypoxia-induced
respiratory alkalosis. J Appl Physiol 2002;92:2097–104.
33. Hughes JMB. Pulmonary gas exchange. In: Hughes JMB,
{ For review see: Zebraski et al, 2000. 88 Pride NB, editors. Lung function tests. Physiological