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Monitoring Fluid Therapy and Complications of Fluid Therapy  387



              TABLE 16-1       Physical Signs                      TABLE 16-3       Physical Findings
                               Associated with                                      Associated with
                               Dehydration                                          Inadequate Tissue
                                                                                    Perfusion
            Percent
            Dehydration             Physical Signs              Assessment               Confounding Factors

            <5            Not detectable                        Mucous Membranes
            5-6           Mild loss of skin elasticity          Pale pink             Vasoconstriction caused by pain or
            6-8           Definite loss of skin elasticity                              anxiety
                          May have dry mucous membranes                                 Anemia
                          May have depressed globes within orbits  Pale               Volume loss overestimated because
            8-10          Persistent skin tent with slow return because                 of vasoconstriction caused by
                           of loss of skin elasticity                                   pain or anxiety
            10-12         Persistent skin tent because of loss of skin  Dark pink or red  Vasodilatation and may be
                           Elasticity                                                   interpreted as normal volume
                          Depressed globes within orbits                              Hemoconcentration may be
                          Dry mucous membranes                                          interpreted as normal volume
                          Signs of perfusion deficits (CRT >2 sec,
                                                                Capillary Refill Time
                           tachycardia)
            12-15        Signs of shock                                               <1 sec may be considered adequate
                         Death                                                          perfusion
                                                                                      Difficult to interpret if peripherally
                                                                                        vasoconstricted because of pain
            Note: The association between % dehydration and circulatory compromise
            must also be considered with rate of fluid loss. Chronic fluid loss may result  or anxiety
            in severe dehydration, but perfusion may be adequate; however, fluid loss
            occurring acutely will result in circulatory collapse at an estimated lower
            level of hydration. Therefore perfusion status cannot consistently be used to  findings. We derive our therapeutic plan using mathemat-
            assess hydration status.                            ical formulas based on an estimated percentage of intra-
            CRT, capillary refill time.
                                                                vascular or tissue loss. Our assessment may not be
                                                                accurate, and therefore the volume of fluid given should
                                                                be titrated to the patient’s needs and the physiologic
              TABLE 16-2       Confounding Factors of           responses to the fluid administered. The extent and inva-
                               Physical Findings                siveness of monitoring used to assess these responses are
                               Associated with                  dependent on the severity of illness and stability of the
                                                                patient, other therapies administered, the interrelation-
                               Dehydration
                                                                ship among variables affecting the hemodynamic profile
            Assessment            Confounding Factors           (e.g., anemia and perfusion, CVP and mechanical venti-
                                                                lation), the availability of various monitoring devices,
            Skin turgor (“tent”)  Young animals with subcutaneous fat  and the level of expertise of the clinician and support staff.
                              Obese animals with subcutaneous fat  This latter point is very important because interpretation
                              Cachectic animals                 of an isolated result, especially when monitoring devices
                              Geriatric animals with loss of tissue  are not frequently used, can complicate treatment
                                elasticity                      regimens.
            Mucous membranes
              Dry             Panting, tachypnea, dyspnea       ENDPOINTS OF FLUID
              Moist           Nauseated, vomiting, drinking     RESUSCITATION
            Position of the globe  Cachexia
            Perfusion status  Affected by rate of fluid loss; chronic  During administration of any fluid, basic monitoring
                                loss may not affect perfusion   techniques should be performed, including heart rate
                                parameters until a large volume is lost  (HR), respiratory rate (RR), pulse pressure, capillary refill
                                                                time (CRT), mucous membrane (MM) color, mentation,
                                                                and temperature and color of the distal limbs and digits.
            MONITORING                                          Although abnormalities in these parameters may not be
                                                                sensitive indicators of hypovolemia, 60  a general goal for
            Assessment of the volume of fluid required to correct  endpoints of resuscitation should be values within the
            fluid deficits in all compartments cannot be accurately  normal range for the size and species of animal with
            derived. Therefore our therapy always is empirical and  recovery to normal mentation and warm, pink digits.
            based on history, physical examination, and laboratory  Monitoring urine production with a goal of 0.5 to
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