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402        FLUID THERAPY


            removed (exceptions are hyperosmolar and vasoactive  15. Ethier MR, Mathews KA, Valverde , et al. Evaluation of the
            solutions), but the limb should be palpated for heat,   efficacy and safety of two sedative-analgesic protocols in
            swelling, and discomfort. If infusion pumps are used and  assisted ventilation in healthy dogs. Am J Vet Res
                                                                    2008;69:1351–9.
            the alarm signals occlusion, the catheter and entry site
                                                                 16. Ferraboli R, Malheiro PS, Abdulkader RC, et al. Anuric
            should be examined carefully.                           acute renal failure caused by dextran-40 administration.
               Destruction of the catheter or administration set will  Ren Fail 1997;19:303–6.
            occur if the animal bites it, and hemorrhage may be a  17. Boucharda J, Mehta RL. Fluid accumulation and acute kid-
                                                                    ney injury: consequence or cause. Curr Opin Crit Care
            complication if this event is not witnessed. Serious hem-
                                                                    2009;15:509–13.
            orrhage also may occur if the connector on an arterial
                                                                 18. Foland JA, Fortenberry JD, Warshaw BL, et al. Fluid over-
            catheter becomes dislodged and may require blood trans-  load before continuous hemofiltration and survival in criti-
            fusion if a large amount of blood loss occurs.          cally ill children: a retrospective analysis. Crit Care Med
               Finally. catheters should not be disconnected when the  2004;32:1771–6.
                                                                 19. Francis A, Martin L, Haldorson GJ, et al. Adverse reactions
            patient is moved. The intravenous line should be clamped
                                                                    suggestive of type III hypersensitivity in six healthy dogs
            as close to the catheter site as possible, the catheter flushed  given human serum albumin. J Am Vet Med Assoc
            witha1 unitheparin/mLsalinesolution,andthebagscar-      2007;230(6):873–9.
            ried with the patient. Disconnecting the lines promotes  20. Gibson GR, Callan MB, Hoffman V. Use of a hemoglobin-
            microbial contamination and the potential for sepsis.   based oxygen-carrying solution in cats: 72 cases (1998-
                                                                    2000). J Am Vet Med Assoc 2002;221:96.
                                                                 21. Gunkel C, Valverde A, Morey T, Hernandez J,
                                                                    Robertson SA. Comparison of non-invasive cardiac output
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