Page 185 - The Toxicology of Fishes

Biotransformation in Fishes 165

TABLE 4.3
CYP2 Gene Family in Fish
Subfamily/Gene Species Refs.

CYP2K Rainbow trout (O. mykiss) Buhler et al. (2000); Cok et al. (1998);
2K1 Killifish (F. heteroclitus) Katchamart et al. (2002); Yang et al. (2000)
2K2 Rainbow trout
2K3-2K5 Zebrafish (D. rerio)
2K6-2K8; 2K16-2K22 Pufferfish (F. rubripes)
2K9-2K11 Pufferfish
2K12-2K15 pseudogenes
CYP2M Rainbow trout Buhler et al. (2000); Cok et al. (1998);
2M1 Katchamart et al. (2002); Yang et al. (1998)
CYP2N Killifish Oleksiak et al. (2000); Peterson and Bain (2004);
2N1 Killifish Schlenk et al. (in press); Vrolijk et al. (1994)
2N2 Scup (S. chrysops)
2N3 Butterfly fish (Chaetodon sp.)
2N4-2N8 Pufferfish
2N9-2N11 Zebrafish
2N13
CYP2P Killifish Oleksiak et al. (2003)
2P1-2P3 Pufferfish
2P4 Pufferfish
2P5 pseudogene Zebrafish
2P6-2P10 Largemouth bass (M. salmoides)
2P11 Atlantic salmon (S. salar)
2P
CYP2R Zebrafish
2R1 Pufferfish
2R1 Pufferfish
2R2-2R3 pseudogenes
CYP2U Zebrafish
2U1 Pufferfish
2U1
CYP2V Zebrafish
CYP2V1
CYP2X1 Catfish (I. punctatus) Schlenk et al. (2002)
CYP2X1 Pufferfish
2X2-2X4 Pufferfish
2X5 pseudogene Zebrafish
2X6-2X11
CYPY Pufferfish
2Y1-2Y2 Zebrafish
2Y3-2Y4
CYPZ Pufferfish
2ZI-2Z2
CYP2AA
2AA1-2AA8
CYP2AD Pufferfish
2AD1 (formerly 2N12) Zebrafish
2AD2-2AD3; 2AD6 Medaka (O. latipes)
2AD4 Three-spined stickleback
2AD5 (Gasterosteus aculeatus)
CYP2AE Zebrafish
2AE1
Note: Genes, gene fragments, and possible pseudogenes were obtained from the cytochrome P450 homepage:
http://drnelson.utmem.edu/CytochromeP450.html.