Page 190 - The Toxicology of Fishes

170 The Toxicology of Fishes

Refs. Celander and Stegeman (1997) Kullman and Hinton (2001) Szklarz and Halpert (1997) — — — Hegelund and Celander (2003) — — — Celander et al. (1996b); Williams et al. (2003) Lao et al. (unpublished) — —
Lee et al. (1998) Kullman et al. (2000)

Detection/ Localization L, IC, PDI, B, INV L, K, I, G, S, B, O Liver microsomes Liver microsomes IC, PDI, INV (low liver) — — — L, K, I, G, S, B, O — — — Liver microsomes — — —

Immunodetection Pos 1, 2 Pos 1, 2 Pos 2 Pos 2 Pos 1, 2 — — — Pos 1 — — — Pos 1, 2 Pos 1 — —

Accession Number O42563 AF105068 AF105018 AF251272 AF267126 PNC PNC PNC AY143428 PNC PNC PNC AJ310471 AAL16897 PNC PNC

CYP3A Gene CYP3A27 CYP3A30 CYP3A38 CYP3A40 CYP3A45 CYP3A48 CYP3A49 CYP3A50P (pseudogene) CYP3A56 CYP3A65 CYP3A68 CYP3A69 CYP3A (partial cds) CYP3A CYP3B1 CYP3B2

Common Name Rainbow trout Killifish Medaka Rainbow trout Pufferfish Killifish Zebrafish Largemouth bass European flounder Carp Pufferfish

CYP3 Phylogeny in Fishes Micropterus salmoides Ctenopharyngodon idella

TABLE 4.4 Species Oncorhynchus mykiss Fundulus heteroclitus Oryzias latipas Oncorhynchus mykiss Fugu rubripes Fundulus heteroclitus Danio rerio Platichthys flesus Fugu rubripes