Page 23 - Feline Cardiology
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14  Section A: Clinical Entities


                                                      Is it syncope?


                                                  Episodic change in mentation and
      Clinical Entities               yes         Tonic-clonic movements of the limbs
                                                   strength (weakness or collapse)


                                                                                 not sure/
                                                       and/or head and neck?
                                                                             infrequent occurrence
                         → Seizures (may                      no
                         be cardiogenic or
                         noncardiogenic)
                                                      Recumbency and      not sure/     Have owners record
                                                      unconsciousness lasts             episodes with home
                                                      >30 seconds?    infrequent occurrence  video
                            → Systemic disorder
                            (anemia, abdominal
                            hemorrhage, polycythemia,  yes    no                                owner able
                            other)
                            → Partial seizures                                              owner not
                                                          SYNCOPE                           able
                            → Narcolepsy/cataplexy
                            → Behavioral abnormality
                                                                            -Systemic disorder
                                                                            (anemia, neoplasia, other)
                                                                   abnormal
                                     Minimum database
                                                                            -Structural heart disease
                        Clinical neurologic exam and fundic exam
                        Electrocardiogram                                   -Pathologic bradycardia
                                                                                rd
                                                                             nd
                        CBC, serum biochemical profile, UA, FeLV/FIV serology;   (2  /3  degree AV block,
                        serum T4 if > 6 years old                           often with poor or absent
                                                                   abnormal
                        Thoracic radiographs                                ventricular escape
                                                                            rhythm; atrial standstill;
                        Echocardiogram
                                                                            sick sinus syndrome)
                                            normal
                                                                            -Pathologic tachycardia
                                     Advanced testing*            abnormal  (rapid, sustained
                                                                            ventricular tachycardia)
                                                     ®
                        Cardiac event monitor – portable (King of Hearts )
                        Cardiac event monitor – extended duration, implanted
                            ®
                        (Reveal )                                  Consider transient extracardiac disorders:
                                                                   -Hypoglycemia
                                            normal
                                                                   -Primary neurologic disease
                       *If only one episode of syncope has occurred, advanced testing may  -Intermittent hypotension (mast cell tumor
                       or may not be performed, based on advantage (additional diagnostic  degranulation, other)
                       information obtained quickly) versus drawbacks (cost, availability of
                       equipment).  Severity of underlying and/or concurrent illness and
                       owner’s concern and perception of risk also are essential factors that
                       determine whether to wait for recurrence — if any — or proceed with
                       advanced testing.  The decision for advanced testing after a single
                       syncopal event is a matter of frank and open discussion between
                       veterinarian and client.
              Figure 2.1.  Diagnostic	algorithm	for	transient	episodes	suspected	of	being	syncope.



              discharge  (peripheral  arterial  hypotension  eliciting  a   tion  (rise  in  arterial  pressure  in  response  to  elevated
              decrease in parasympathetic tone), the central nervous   intracranial/cerebrospinal fluid pressure) (Guyton and
              system  ischemic  response  (sympathetically  mediated   Hall 2006). The nonchalance with which cats walk away
              arterial constriction originating from hypercarbia in the   from a syncopal episode and resume their activities is
              vasomotor center of the medulla), and the Cushing reac-  often striking to owners. A substantial exception is the
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